Position sensitivity in the visual word form area.

Proceedings of the National Academy of Sciences of the United States of America
Andreas M RauscheckerBrian A Wandell

Abstract

Seeing words involves the activity of neural circuitry within a small region in human ventral temporal cortex known as the visual word form area (VWFA). It is widely asserted that VWFA responses, which are essential for skilled reading, do not depend on the visual field position of the writing (position invariant). Such position invariance supports the hypothesis that the VWFA analyzes word forms at an abstract level, far removed from specific stimulus features. Using functional MRI pattern-classification techniques, we show that position information is encoded in the spatial pattern of VWFA responses. A right-hemisphere homolog (rVWFA) shows similarly position-sensitive responses. Furthermore, electrophysiological recordings in the human brain show position-sensitive VWFA response latencies. These findings show that position-sensitive information is present in the neural circuitry that conveys visual word form information to language areas. The presence of position sensitivity in the VWFA has implications for how word forms might be learned and stored within the reading circuitry.

References

Jan 1, 1990·Spatial Vision·T A Nazir, J K O'Regan
Jan 1, 1972·Journal of Neurophysiology·C G GrossD B Bender
Mar 1, 1980·Brain : a Journal of Neurology·E K Warrington, T Shallice
Aug 29, 1995·Proceedings of the National Academy of Sciences of the United States of America·R MalachR B Tootell
Nov 17, 1994·Nature·A C NobreG McCarthy
Jan 1, 1997·Spatial Vision·D H Brainard
Aug 10, 1999·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G H Glover
Nov 5, 1999·Brain : a Journal of Neurology·A TarkiainenR Salmelin
Dec 29, 2000·Nature Neuroscience·M Riesenhuber, T Poggio
Apr 27, 2001·Vision Research·K Grill-SpectorN Kanwisher
Jun 27, 2001·Nature Neuroscience·S DehaeneD Rivière
Apr 19, 2002·Brain : a Journal of Neurology·Laurent CohenStanislas Dehaene
Jul 20, 2002·Journal of Cognitive Neuroscience·N MolkoS Dehaene
Jul 16, 2003·Trends in Cognitive Sciences·Bruce D. McCandlissStanislas Dehaene
Dec 4, 2003·Journal of Vision·Robert F DoughertyBrian A Wandell
Feb 18, 2004·Brain and Language·Tatjana A NazirRam Frost
Apr 28, 2004·NeuroImage·Laurent Cohen, Stanislas Dehaene
Jul 28, 2004·NeuroImage·Kristen PammerPiers L Cornelissen
Dec 8, 2004·Brain and Language·Mary RudnerKenneth Hugdahl
Jun 14, 2005·Trends in Cognitive Sciences·Stanislas DehaeneFabien Vinckier
Jul 19, 2005·Nature Neuroscience·Alyssa A BrewerBrian A Wandell
Aug 24, 2005·Nature Neuroscience·David D CoxJames J DiCarlo
Nov 8, 2005·Science·Chou P HungJames J DiCarlo
Mar 16, 2006·Proceedings of the National Academy of Sciences of the United States of America·Nikolaus KriegeskortePeter Bandettini
Jul 15, 2006·Journal of Cognitive Neuroscience·Joseph T DevlinPaul M Matthews
Sep 8, 2006·NeuroImage·Jeffrey R BinderLori Buchanan
Dec 22, 2006·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jonas Larsson, David J Heeger
Oct 30, 2007·Neuron·Brian A WandellAlyssa A Brewer
Nov 3, 2007·NeuroImage·Serge O Dumoulin, Brian A Wandell
Dec 15, 2007·Vision Research·Seyed-Reza Afraz, Patrick Cavanagh
Feb 12, 2008·Trends in Cognitive Sciences·Dwight J KravitzChris I Baker
Sep 2, 2008·Trends in Cognitive Sciences·Jonathan GraingerStéphane Dufau
Oct 3, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·David D Cox, James J DiCarlo
Oct 28, 2008·Brain : a Journal of Neurology·Andrew J O Whitehouse, Dorothy V M Bishop
Dec 17, 2008·Annals of the New York Academy of Sciences·José M MaisogGuinevere F Eden
Aug 28, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michael J ArcaroSabine Kastner

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Citations

May 31, 2012·Proceedings of the National Academy of Sciences of the United States of America·Rainer Goebel
Oct 8, 2013·PLoS Computational Biology·Thomas Hannagan, Jonathan Grainger
Jan 15, 2014·PloS One·Thomas HannaganJonathan Grainger
Mar 16, 2013·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Giovanni Berlucchi
Jan 1, 2014·Trends in Cognitive Sciences·Manuel CarreirasRam Frost
Feb 24, 2015·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Svenja CaspersKarl Zilles
Aug 19, 2014·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Ori OssmyRoy Mukamel
Jan 10, 2014·Brain and Language·Iain DeWitt, Josef P Rauschecker
Oct 25, 2016·Brain and Cognition·Giovanna MolloElizabeth Jefferies
Sep 25, 2016·Cerebral Cortex·Libo ZhaoGui Xue
Apr 12, 2017·Neuropsychologia·Lars StrotherTutis Vilis
Oct 31, 2018·Human Brain Mapping·Ronald K Chu, Jed A Meltzer
Mar 30, 2019·Journal of Vision·Ying-Zi XiongGordon E Legge
Apr 3, 2019·Journal of Cognitive Neuroscience·Zhiheng ZhouLars Strother
May 27, 2014·PloS One·Liwei King BlackburneJohn D E Gabrieli
Apr 10, 2019·Proceedings of the National Academy of Sciences of the United States of America·Alex L WhiteJason D Yeatman
May 10, 2019·Proceedings of the National Academy of Sciences of the United States of America·Lars Strother
Sep 24, 2020·Scientific Reports·Elham Barzegaran, Anthony M Norcia
May 29, 2018·The Quarterly Journal of Experimental Psychology : QJEP·Hagit Magen
Dec 19, 2020·Psychological Research·Simone SulpizioRemo Job
Jan 31, 2021·Brain and Language·Sung Jun JooJason D Yeatman
Mar 12, 2021·Journal of Vision·Dina V PopovkinaGeoffrey M Boynton
Feb 24, 2018·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Adélaïde de HeeringRégine Kolinsky
Jun 25, 2021·Annual Review of Vision Science·Jason D Yeatman, Alex L White
Oct 13, 2021·Brain Structure & Function·Sendy CaffarraJason D Yeatman

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