Positioning of the Motility Machinery in Halophilic Archaea

MBio
Zhengqun LiSonja-Verena Albers

Abstract

Bacteria and archaea exhibit tactical behavior and can move up and down chemical gradients. This tactical behavior relies on a motility structure, which is guided by a chemosensory system. Environmental signals are sensed by membrane-inserted chemosensory receptors that are organized in large ordered arrays. While the cellular positioning of the chemotaxis machinery and that of the flagellum have been studied in detail in bacteria, we have little knowledge about the localization of such macromolecular assemblies in archaea. Although the archaeal motility structure, the archaellum, is fundamentally different from the flagellum, archaea have received the chemosensory machinery from bacteria and have connected this system with the archaellum. Here, we applied a combination of time-lapse imaging and fluorescence and electron microscopy using the model euryarchaeon Haloferax volcanii and found that archaella were specifically present at the cell poles of actively dividing rod-shaped cells. The chemosensory arrays also had a polar preference, but in addition, several smaller arrays moved freely in the lateral membranes. In the stationary phase, rod-shaped cells became round and chemosensory arrays were disassembled. The positioning o...Continue Reading

References

May 18, 2020·Molecular Microbiology·Zhengqun LiTessa E F Quax
Mar 10, 2020·FEMS Microbiology Reviews·Morgan BeebyDavid R Mitchell
Mar 27, 2020·MBio·Mohd Farid Abdul-HalimMechthild Pohlschroder

Citations

Mar 1, 1991·Journal of Bacteriology·W MarwanD Oesterhelt
Oct 27, 1972·Nature·Howard C Berg, D A Brown
Jul 15, 1984·Journal of Molecular Biology·M Alam, Dieter Oesterhelt
Oct 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·M WelchM Eisenbach
May 17, 1996·Journal of Molecular Biology·J Rudolph, Dieter Oesterhelt
Jan 19, 2002·Nature Structural Biology·Ian J GriswoldFrederick W Dahlquist
Sep 17, 2002·Proceedings of the National Academy of Sciences of the United States of America·Victor Sourjik, Howard C Berg
Feb 10, 2004·Applied and Environmental Microbiology·Thorsten AllersRobert G Lloyd
Jun 10, 2004·Microbiology and Molecular Biology Reviews : MMBR·Hendrik Szurmant, George W Ordal
Mar 15, 2006·Cell·Edgar HuitemaPatrick H Viollier
Apr 20, 2006·Nature Structural & Molecular Biology·Sang-Youn ParkBrian R Crane
Mar 3, 2007·The EMBO Journal·Sebastian ThiemVictor Sourjik
Nov 17, 2007·Current Opinion in Microbiology·Sonia L Bardy, Janine R Maddock
May 15, 2008·Molecular Microbiology·Sebastian Thiem, Victor Sourjik
May 17, 2008·Nature Reviews. Microbiology·Fabienne F V Chevance, Kelly T Hughes
Mar 18, 2009·BMC Microbiology·Matthias SchlesnerDieter Oesterhelt
Sep 25, 2009·Molecular Microbiology·Iryna BulyhaLotte Søgaard-Andersen
May 5, 2010·Proceedings of the National Academy of Sciences of the United States of America·Mayukh K SarkarDavid Blair
Jul 1, 2010·Science Signaling·Kristin Wuichet, Igor B Zhulin
Feb 2, 2011·Nature Reviews. Microbiology·Steven L PorterJudith P Armitage
May 25, 2011·Proceedings of the National Academy of Sciences of the United States of America·Mingshan Li, Gerald L Hazelbauer
Feb 23, 2012·Proceedings of the National Academy of Sciences of the United States of America·Ariane BriegelBrian R Crane
Apr 13, 2012·Proceedings of the National Academy of Sciences of the United States of America·Mark A J RobertsJudith P Armitage
May 5, 2012·Proceedings of the National Academy of Sciences of the United States of America·Jun LiuWilliam Margolin
May 23, 2012·Trends in Microbiology·Ken F Jarrell, Sonja-Verena Albers
Jun 8, 2012·Trends in Microbiology·Joe Lutkenhaus
Aug 30, 2012·Nature Methods·Caroline A SchneiderKevin W Eliceiri
Nov 23, 2012·BMC Microbiology·Matthias SchlesnerDieter Oesterhelt
Apr 23, 2013·Molecular Microbiology·Barbara I Kazmierczak, David R Hendrixson
Nov 5, 2013·Journal of Bacteriology·Carmen FriedrichLotte Søgaard-Andersen
Dec 18, 2013·Molecular Microbiology·Rajesh ShahapureRemus Th Dame
Jan 1, 2014·Proceedings of the National Academy of Sciences of the United States of America·Simon RinggaardMatthew K Waldor
Dec 24, 2014·Nature·Iain G DugginJan Löwe
Jan 13, 2015·Environmental Microbiology Reports·Ariane BriegelGrant J Jensen
Mar 4, 2015·Proceedings of the National Academy of Sciences of the United States of America·Jan S SchuhmacherGert Bange
Apr 4, 2015·Trends in Microbiology·John S ParkinsonJoseph J Falke
Apr 7, 2015·Trends in Microbiology·Christopher W Jones, Judith P Armitage
Jul 22, 2015·FEMS Microbiology Reviews·Jan S SchuhmacherGert Bange
Nov 3, 2015·Nature Communications·H StrahlL W Hamoen
Mar 10, 2016·Proceedings of the National Academy of Sciences of the United States of America·Germán E PiñasJohn S Parkinson

Related Concepts

Russula archaea
Sensory Perception of Chemical Stimulus
Membrane
Cell Polarity
Cell Motility
Regulation of Biological Process
Protoplasm
Time-Lapse Imaging
Chemotaxis
Anatomical Space Structure

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Sexual Dimorphism in Neurodegeneration

There exist sex differences in neurodevelopmental and neurodegenerative disorders. For instance, multiple sclerosis is more common in women, whereas Parkinson’s disease is more common in men. Here is the latest research on sexual dimorphism in neurodegeneration

HLA Genetic Variation

HLA genetic variation has been found to confer risk for a wide variety of diseases. Identifying these associations and understanding their molecular mechanisms is ongoing and holds promise for the development of therapeutics. Find the latest research on HLA genetic variation here.

Super-resolution Microscopy

Super-resolution microscopy is the term commonly given to fluorescence microscopy techniques with resolutions that are not limited by the diffraction of light. Here are the latest discoveries pertaining to super-resolution microscopy.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells.

Brain Lower Grade Glioma

Low grade gliomas in the brain form from oligodendrocytes and astrocytes and are the slowest-growing glioma in adults. Discover the latest research on these brain tumors here.

CD4/CD8 Signaling

Cluster of differentiation 4 and 8 (CD8 and CD8) are glycoproteins founds on the surface of immune cells. Here is the latest research on their role in cell signaling pathways.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

© 2020 Meta ULC. All rights reserved