Positive direct antiglobulin test in COVID-19 patients: Decision-making process.

Transfusion clinique et biologique : journal de la Société française de transfusion sanguine
J CaboV Deneys

Abstract

In this unprecedented crisis of severe acute respiratory syndrome coronavirus 2 and its associated coronavirus disease 2019 (COVID-19), polymerase chain reaction and then serological testing platforms have been massively developed to face the important screening demand. Polymerase chain reaction and serological testing platforms are not the only actors impacted by the crisis, transfusion services are facing important difficulties. A positive direct antiglobulin test is frequently observed for patients encountering COVID-19. Patients with severe symptoms may develop anaemia and become good candidates for blood transfusions. The interpretation of a positive direct antiglobulin test for patients recently transfused and suffering from COVID-19 is complex. The differentiation between COVID-19 induced antibodies and possible associated transfusion alloantibodies is therefore crucial. In this context, the elution technique incorporated in an appropriate decision-making process plays its full role. This intricate topic is presented through a case report followed by literature review and finally decision-making process for COVID-19 patients necessitating red blood cells administration.

References

May 1, 1977·American Journal of Clinical Pathology·B S BerlinD Green
Aug 1, 1992·American Journal of Clinical Pathology·A M Johnson
Jan 1, 1988·Vox Sanguinis·P JamesG G Tozzo
Sep 1, 1983·Annals of Internal Medicine·R StrikasJ R Lentino
Jul 1, 1982·British Journal of Haematology·S Abdalla, D J Weatherall
May 22, 2001·AIDS Patient Care and STDs·M W Saif
Jul 24, 2001·Journal of Pediatric Hematology/oncology·J C MurrayA B Morad
Jul 16, 2002·American Journal of Hematology·Prasad Rao KoduriPetros Nikolinakos
Jul 1, 1965·British Journal of Haematology·W J JENKINSR L CARTER
Sep 10, 2004·Journal of Clinical Laboratory Analysis·M C Z NovarettiD A F Chamone
May 29, 2007·Indian Journal of Pediatrics·Neerja AgrawalM Mahapatra
Jul 7, 2009·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Fahmi Yousef Khan, Mohamed A yassin
Jun 22, 2010·Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases·Toru Shizuma
Sep 17, 2010·The American Journal of Medicine·Yoland SchoindreAude Servais
Feb 15, 2012·Blood Reviews·Sigbjørn Berentsen, Geir E Tjønnfjord
May 9, 2012·American Journal of Hematology·Nicole D ZantekClaudia S Cohn
Oct 24, 2013·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Adam S JohnsonGarrett S Booth
Oct 2, 2014·International Journal of Laboratory Hematology·M A AlzateJ M González
Jun 5, 2015·Hematology/oncology Clinics of North America·Sigbjørn BerentsenGeir E Tjønnfjord
Jan 10, 2017·Transfusion Medicine Reviews·Shaun LawickiAmy A Powers
Jan 31, 2017·Archives of Pathology & Laboratory Medicine·Victoria Parker, Christopher A Tormey
Apr 4, 2018·JAMA : the Journal of the American Medical Association·Brady SteinLuke Hillman
Apr 24, 2018·Journal of Pediatric Hematology/oncology·Elpis MantadakisAggelos Tsalkidis
Sep 13, 2018·JAMA : the Journal of the American Medical Association·Brett G FischerArthur T Evans
Apr 7, 2020·Vox Sanguinis·Meghan DelaneyUNKNOWN Biomedical Excellence for Safer Transfusion (BEST) Collaborative
Apr 18, 2020·Journal of Hematology·Richard Jesse DurranceBhupinder B Singh
May 6, 2020·British Journal of Haematology·Chris LopezThomas G DeLoughery
May 7, 2020·British Journal of Haematology·Gregory LazarianFlorence Cymbalista
May 15, 2020·Clinica Chimica Acta; International Journal of Clinical Chemistry·Guoguang Lu, Jing Wang
May 27, 2020·British Journal of Haematology·Francesca AngileriFrancesco Cappello
May 28, 2020·British Journal of Haematology·Emily ZagorskiDaniel Forman
Jun 15, 2020·Autoimmunity Reviews·Francesca AngileriFrancesco Cappello
Jun 17, 2020·Annals of Hematology·Antoine CapesPierre-François Laterre
Jun 28, 2020·Annals of Hematology·Tessa HuscenotUNKNOWN APHP Lariboisière COVID Group

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anemia

Anemia develops when your blood lacks enough healthy red blood cells. Anemia of inflammation (AI, also called anemia of chronic disease) is a common, typically normocytic, normochromic anemia that is caused by an underlying inflammatory disease. Here is the latest research on anemia.