Positive effects of protein restriction in patients with chronic kidney disease

Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation
Sintra EyreBörje Haraldsson

Abstract

The potential benefit or harm of low-protein diets (LPDs) for patients with chronic kidney disease has been debated. This study sought to investigate the effects of treatment with LPDs on nutritional markers, morbidity, and survival during subsequent dialysis. A second objective was to evaluate the effect of LPDs on renal function and the start of dialysis. This was a retrospective study of medical records. The setting was an outpatient nephrology and dialysis clinic. One-hundred twenty-two renal patients were recruited from the central dialysis registry of one clinic. The patients had been followed by a nephrologist for > or =6 months before dialysis. Sixty-one patients were treated with LPDs, and an equal number of control patients not treated with LPDs were matched for sex, age, dialysis modality, diabetes, and start of dialysis. Main outcome measures included weight and weight change, serum albumin, glomerular filtration rate, morbidity, and mortality. There was less mean weight loss in the LPD group the year before dialysis (0.14 kg/month, compared with the control group at 0.36 kg/month, P < .05). The level of serum albumin was higher in the LPD group at the start of dialysis (P < .01). The mean rate of progression during...Continue Reading

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Citations

Nov 8, 2013·Journal of Diabetes Research·Fahimeh Haghighatdoost, Leila Azadbakht
May 10, 2012·Revista da Associação Médica Brasileira·Gláucia Thaise Coimbra de OliveiraMaria Isabel Toulson Davisson Correia
Dec 1, 2012·Journal of Renal Nutrition : the Official Journal of the Council on Renal Nutrition of the National Kidney Foundation·Juliana Giglio Paes-BarretoCarla Maria Avesani
Jul 23, 2013·Journal of the American Medical Directors Association·Jürgen BauerYves Boirie
Feb 10, 2016·PloS One·Ana Carolina RomeroFernando Neves Nogueira
Jul 21, 2016·BMC Nephrology·Sintra EyreJuan-Jesus Carrero

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