Positive predictive value of infective endocarditis in the Danish National Patient Registry: a validation study

Epidemiology and Infection
Lauge ØstergaardMorten Schmidt

Abstract

The positive predictive value of an infective endocarditis diagnosis is approximately 80% in the Danish National Patient Registry. However, since infective endocarditis is a heterogeneous disease implying long-term intravenous treatment, we hypothesiszed that the positive predictive value varies by length of hospital stay. A total of 100 patients with first-time infective endocarditis in the Danish National Patient Registry were identified from January 2010 - December 2012 at the University hospital of Aarhus and regional hospitals of Herning and Randers. Medical records were reviewed. We calculated the positive predictive value according to admission length, and separately for patients with a cardiac implantable electronic device and a prosthetic heart valve using the Wilson score method. Among the 92 medical records available for review, the majority of the patients had admission length ⩾2 weeks. The positive predictive value increased with length of admission. In patients with admission length <2 weeks the positive predictive value was 65% while it was 90% for admission length ⩾2 weeks. The positive predictive value was 81% for patients with a cardiac implantable electronic device and 87% for patients with a prosthetic valve...Continue Reading

References

Sep 14, 2007·Scandinavian Journal of Infectious Diseases·François DelahayeUNKNOWN AEPEI Group
Dec 25, 2007·Progress in Cardiovascular Diseases·Gilbert HabibJean-François Avierinos
Mar 9, 2012·Scandinavian Cardiovascular Journal : SCJ·Thomas Andersen RixAlbert Marni Joensen
Apr 9, 2015·The New England Journal of Medicine·Sanjit S JollyUNKNOWN TOTAL Investigators
Nov 26, 2015·Clinical Epidemiology·Morten SchmidtHenrik Toft Sørensen
Jun 25, 2016·European Journal of Internal Medicine·Purnima ErichsenNiels Eske Bruun
Oct 25, 2016·International Journal of Cardiology·Charlie TanNeill K J Adhikari

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Citations

Oct 8, 2019·The Journal of Clinical Endocrinology and Metabolism·Signe E J HansenBørge G Nordestgaard
Aug 25, 2020·Circulation·Christopher J AllenBernard D Prendergast
May 31, 2019·European Heart Journal·Lauge ØstergaardEmil Loldrup Fosbøl
Jun 15, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Christine Falk KleinKasper Karmark Iversen
Jul 21, 2020·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jeppe Kofoed PetersenLauge Østergaard
Oct 19, 2020·International Journal of Cardiology·Andreas Dalsgaard JensenEmil Loldrup Fosbøl
Apr 10, 2021·Journal of the American College of Cardiology·Adelina YafasovaJawad H Butt
May 27, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ulrika Snygg-MartinZacharias Mandalenakis
Jul 18, 2021·BMC Infectious Diseases·Sandra Chamat-HedemandAnders Dahl
Aug 20, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Michelle D S SchmiegelowSøren S Schmiegelow

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