PMID: 9165413Jun 1, 1997Paper

Positive pressure inspiration differentially affects right and left ventricular outputs in postoperative cardiac surgery patients

Journal of Critical Care
P C van den BergM R Pinsky

Abstract

The purpose of this study was to determine the dynamic changes in right ventricular (RV) and left ventricular (LV) output during positive airway pressure inspiratory hold maneuvers so as to characterize the interaction of processes in creating steady-state cardiac output during positive pressure ventilation. We examined the disparity of RV and LV outputs at 5 seconds (early) and 20 seconds (late) into a 24-second inspiratory hold maneuver in 14 subjects in the intensive care unit immediately following coronary artery bypass surgery. RV output was measured by the thermodilution technique, whereas LV output was measured by the arterial pulse contour method. RV and LV volumes were also measured by thermal and radionuclide ejection fraction techniques, respectively. As P(aw) was progressively increased from 0 to 20 cm H2O in sequential inspiratory hold maneuvers, both RV and LV outputs changed differently both at 5 seconds and 20 seconds into the inspiratory hold maneuvers. When expressed as change in cardiac output (L/min) for every cm H2O P(aw) increase relative to end-expiratory values, RV output increased at 5 seconds (0.05 +/- 0.15 L/min) then decreased at 20 seconds (-0.08 +/- 0.21, P < .05). LV output decreased slightly at 5...Continue Reading

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Citations

Jul 19, 2012·Journal of Clinical Monitoring and Computing·Samir G SakkaAzriel Perel
Sep 11, 2008·British Journal of Anaesthesia·N Soni, P Williams
Feb 27, 2010·Anesthesia and Analgesia·Daniel A ReuterHolger K Eltzschig
Aug 13, 2005·Intensive Care Medicine·Jonas NielsenAnders Larsson
Apr 20, 2014·Critical Care Medicine·Benno LansdorpPeter Pickkers
Jan 8, 2000·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·J O AulerL M Malbouisson
Jul 17, 2016·American Journal of Physiology. Heart and Circulatory Physiology·David BergerJukka Takala
Mar 1, 2017·European Journal of Applied Physiology·Tanja MijacikaPer Lav Madsen

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