Positive pressure ventilation treatment reduces plasma levels of amino terminal-pro brain natriuretic peptide in congestive heart failure patients with sleep apnea

Circulation Journal : Official Journal of the Japanese Circulation Society
Zhi-hui ZhaoYue-jin Yang

Abstract

The purpose of the present study was to assess the short-term effects of positive pressure ventilation (PPV) on plasma amino terminal-pro brain natriuretic peptide (NT-proBNP) levels in patients with congestive heart failure (CHF) and sleep apnea (SA). Polysomnography was performed in 105 CHF patients. Twenty-six patients with CHF and SA were randomly assigned to a control group or a PPV group. Patients in the higher New York Heart Association classes had higher plasma levels of NT-proBNP. The plasma NT-proBNP concentration in the PPV group decreased. Plasma NT-proBNP levels reflect the severity of CHF, and PPV can decrease plasma NT-proBNP levels in patients with CHF and SA.

References

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Aug 21, 2003·American Journal of Respiratory and Critical Care Medicine·Justin C T PepperellRobert J O Davies
Feb 28, 2004·European Journal of Heart Failure·Mark Richards, Richard W Troughton
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Nov 12, 2005·The New England Journal of Medicine·T Douglas BradleyUNKNOWN CANPAP Investigators

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Citations

Oct 9, 2009·Sleep & Breathing = Schlaf & Atmung·Nilüfer CifçiErhan Ekinci
Oct 30, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Yoshihiko SeinoUNKNOWN CHF-HOT
Jun 26, 2008·Circulation Journal : Official Journal of the Japanese Circulation Society·Tomotaka DohiShin-Ichi Momomura
Nov 23, 2006·Journal of Sleep Research·Justin PepperellRobert Davies
Dec 5, 2019·The Cochrane Database of Systematic Reviews·Shuhei YamamotoRintaro Mori
Jul 2, 2017·Current Heart Failure Reports·Ying Y Zhao, Reena Mehra

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