Positive selection of synonymous mutations in vesicular stomatitis virus

Journal of Molecular Biology
I S NovellaBonnie E Ebendick-Corpus

Abstract

Prevailing evolutionary forces are typically deduced from the pattern of differences in synonymous and non-synonymous mutations, under the assumption of neutrality in the absence of amino acid change. We determined the complete sequence of ten vesicular stomatitis virus populations evolving under positive selection. A significant number of the mutations occurred independently in two or more strains, a process known as parallel evolution, and a substantial fraction of the parallel mutations were silent. Parallel evolution was also identified in non-coding regions. These results indicate that silent mutations can significantly contribute to adaptation in RNA viruses, and relative frequencies of synonymous and non-synonymous substitutions may not be useful to resolve their evolutionary history.

References

Apr 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·J C de la TorreJ J Holland
Aug 1, 1990·Journal of Virology·D R MillsB D Binderow
Dec 1, 1994·AIDS Research and Human Retroviruses·P KasperK E Schneweis
Feb 1, 1994·Journal of Virology·N TakedaK Miyamura
Dec 31, 1997·Genetics·J J BullI J Molineux
Jun 27, 1998·Molecular Microbiology·J J BullI J Molineux
Aug 6, 1998·The Journal of Endocrinology·D A Day, M F Tuite
Mar 31, 1999·Proceedings of the National Academy of Sciences of the United States of America·D PapadopoulosM Blot
Jun 11, 1999·Journal of Virology·P Simmonds, D B Smith
May 24, 2001·Molecular Biology and Evolution·G M JenkinsE C Holmes
Jul 20, 2001·Journal of Virology·J QuerI S Novella
Dec 26, 2001·Bioinformatics·S KumarM Nei
Sep 6, 2002·Biochimica Et Biophysica Acta·John N BarrGail W Wertz
Oct 5, 2002·Nucleic Acids Research·David J LynnDonal A Hickey
Oct 16, 2002·Trends in Parasitology·Donald R Forsdyke
Nov 26, 2002·Proceedings of the National Academy of Sciences of the United States of America·Maitreya J DunhamDavid Botstein
Mar 26, 2003·Bioinformatics·Steve WoolleyDavid A McClellan
Jun 14, 2003·Journal of Virology·Leonid Gitlin, Raul Andino
Jun 26, 2003·Nucleic Acids Research·Michael Zuker
Sep 15, 2004·Journal of Molecular Biology·I S Novella, B E Ebendick-Corpus
Jan 1, 2002·Journal of Virology·Esteban Domingo

❮ Previous
Next ❯

Citations

Oct 13, 2010·Nature Reviews. Microbiology·Kim M PepinJames O Lloyd-Smith
Mar 21, 2008·Molecular Biology and Evolution·Susanna K RemoldPaul E Turner
Jul 21, 2011·Molecular Biology and Evolution·José M CuevasRafael Sanjuán
Jun 14, 2013·Open Biology·Libertad García-Villada, John W Drake
Feb 26, 2010·Journal of Virology·Isabel S NovellaClaus O Wilke
Feb 22, 2008·Journal of Virology·Ranendra N DuttaIsabel S Novella
Jan 18, 2012·Journal of Molecular Microbiology and Biotechnology·Isabel S NovellaClaus O Wilke
Nov 28, 2007·PLoS Pathogens·Agnès Pinel-GalziDenis Fargette
Oct 13, 2010·Theoretical Population Biology·Mark D Rendel
Jul 23, 2008·Journal of Molecular Biology·John B PresloidIsabel S Novella
Jun 4, 2014·Evolution; International Journal of Organic Evolution·Julia HillungSantiago F Elena
Sep 15, 2004·Journal of Molecular Biology·I S Novella, B E Ebendick-Corpus
Jan 29, 2010·The Journal of General Virology·Sarah D Smith-TsurkanIsabel S Novella
Apr 19, 2008·The Journal of General Virology·Tarja SironenAlexander Plyusnin
Oct 25, 2016·Virus Evolution·Pablo Hernández-AlonsoRafael Sanjuán
Feb 11, 2015·Molecular Biology and Evolution·José M CuevasSantiago F Elena
Feb 26, 2016·Molecular Biology and Evolution·Deepa AgasheChristopher J Marx
May 23, 2009·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·I V KuzminC E Rupprecht
Jul 25, 2014·Journal of Virology·Akiko KashiwagiTetsuya Yomo
Jan 20, 2017·Journal of Virology·Nicole Lewis-RogersFrederick R Adler
May 31, 2018·Scientific Reports·Alexander KulaCatherine Putonti
Sep 30, 2020·Archives of Microbiology·T G VillaA Sánchez-Pérez
Oct 19, 2014·G3 : Genes - Genomes - Genetics·Zachary L FullerStephen W Schaeffer
Mar 7, 2021·Viruses·Maria Celeste Torres On Behalf Of ZikAction Consortium
May 28, 2021·Virus Evolution·Ahmed Al-ZaherRafael Sanjuán

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.