PMID: 18199342Jan 18, 2008Paper

Positive surgical margins at radical prostatectomy: importance of intra-operative bladder neck frozen sections

International Braz J Urol : Official Journal of the Brazilian Society of Urology
Kogenta NakamuraCharles J Rosser

Abstract

To determine if intraoperative frozen sections of the bladder neck during radical prostatectomy (RP) could decrease the incidence of final positive surgical margins at the bladder neck. This prospective cohort study included 51 consecutive men who underwent anatomic RP at University of Florida & Shands Jacksonville. All patients had intraoperative frozen section of bladder neck sent for analysis. Preoperative, operative, and postoperative data were collected and analyzed. Outcome measures were intraoperative bladder neck margin status, final pathologic bladder neck margin status, and postoperative urinary complications. Median follow-up for the 51 patients was 22 months. The final positive surgical margin rate was 20% (10 patients). An additional three patients had positive surgical margins at the bladder neck intraoperatively. These patients then had a wider resection of the affected bladder neck until the frozen sections were negative for cancer or prostatic tissue. Final pathologic evaluation of bladder neck margin was negative for tumor or persistent prostatic tissue in all 51 men. With intra-operative frozen sections, we were able to obtain a negligible positive bladder neck margin rate. Surgeons who are still on the learn...Continue Reading

References

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Citations

Mar 17, 2009·BMC Research Notes·Kazunori NamikiCharles J Rosser
May 23, 2015·Asian Journal of Andrology·Abdullah Erdem Canda, Mevlana Derya Balbay
Jun 21, 2007·Neurourology and Urodynamics·Alfred E BentRichard C Bump
Nov 27, 2007·International Journal of Urology : Official Journal of the Japanese Urological Association·Mizuaki SakuraKazunori Kihara
Sep 25, 2007·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·A Bossi
Mar 6, 2004·International Journal of Radiation Oncology, Biology, Physics·Richard K ValicentiLeonard G Gomella

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