Positron emission tomography imaging of prostate cancer.

Amino Acids
Hao HongWeibo Cai

Abstract

Prostate cancer (PCa) is the second leading cause of cancer death among men in the United States. Positron emission tomography (PET), a non-invasive, sensitive, and quantitative imaging technique, can facilitate personalized management of PCa patients. There are two critical needs for PET imaging of PCa, early detection of primary lesions and accurate imaging of PCa bone metastasis, the predominant cause of death in PCa. Because the most widely used PET tracer in the clinic, (18)F-fluoro-2-deoxy-2-D-glucose ((18)F-FDG), does not meet these needs, a wide variety of PET tracers have been developed for PCa imaging that span an enormous size range from small molecules to intact antibodies. In this review, we will first summarize small-molecule-based PET tracers for PCa imaging, which measure certain biological events, such as cell membrane metabolism, fatty acid synthesis, and receptor expression. Next, we will discuss radiolabeled amino acid derivatives (e.g. methionine, leucine, tryptophan, and cysteine analogs), which are primarily based on the increased amino acid transport of PCa cells. Peptide-based tracers for PET imaging of PCa, mostly based on the bombesin peptide and its derivatives which bind to the gastrin-releasing pep...Continue Reading

References

Jan 1, 1979·Urologic Radiology·J M Price, A J Davidson
Sep 12, 1979·Biochemical and Biophysical Research Communications·T J McDonaldV Mutt
Nov 1, 1970·The Journal of Pharmacy and Pharmacology·V ErspamerM Inselvini
Jan 23, 1996·Proceedings of the National Academy of Sciences of the United States of America·R E CarterJ T Coyle
Jan 1, 1997·The Prostate·R J BarrenG P Murphy
Mar 21, 1998·Proceedings of the National Academy of Sciences of the United States of America·R E ReiterO N Witte
Mar 12, 1998·International Journal of Cancer. Journal International Du Cancer·M F BartholdiR I Feldman
Jun 25, 1998·Nuclear Medicine and Biology·E K PauwelsB Mazière
Oct 8, 1998·The New England Journal of Medicine·M A EisenbergerB A Lowe
Nov 17, 1998·The Journal of Urology·J H Texter, C E Neal
Dec 14, 1999·The American Journal of Pathology·M Gugger, J C Reubi
Nov 1, 2000·Cell·J Schlessinger
Feb 27, 2001·Current Opinion in Urology·J Rørvik, S Haukaas
Aug 16, 2001·European Journal of Nuclear Medicine·S M Okarvi
Apr 27, 2002·European Journal of Nuclear Medicine and Molecular Imaging·Peter LavermanWim J G Oyen
Aug 13, 2002·Current Opinion in Urology·Dana Mathews, Orhan K Oz
Sep 5, 2002·Nature Reviews. Cancer·Sanjiv Sam Gambhir
Sep 25, 2002·European Journal of Nuclear Medicine and Molecular Imaging·Igle J de JongWillem Vaalburg
Oct 18, 2002·Biopolymers·Sylvie Froidevaux, Alex N Eberle
Oct 1, 2003·Clinical Positron Imaging : Official Journal of the Institute for Clinical P.E.T·Homer A. MacapinlacSteven M. Larson
Oct 23, 2003·Seminars in Oncology·David B SolitNeal Rosen
Mar 23, 2004·Current Topics in Medicinal Chemistry·John C Reader
Apr 8, 2004·Current Opinion in Urology·Suzie J Otto, Harry J de Koning
Apr 15, 2004·Endocrine Reviews·Cynthia A Heinlein, Chawnshang Chang
Dec 14, 2004·The Journal of Urology·György TóthCsaba Tóth
Dec 14, 2004·The Journal of Urology·Sandi A KweeJehoon P Ko
Feb 24, 2005·European Journal of Nuclear Medicine and Molecular Imaging·Farrokh DehdashtiMichael J Welch
Apr 6, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Jacek Pinski, Tanya B Dorff
Apr 9, 2005·Current Opinion in Urology·Stephen A BrassellDavid G McLeod
May 4, 2005·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Michael J MorrisHoward I Scher
May 11, 2005·Clinical Prostate Cancer·D Bruce SodeeGeorge Bakale
Jun 3, 2005·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Catherine A FossMartin G Pomper
Jun 30, 2005·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Ronald E Weiner, Mathew L Thakur
Jul 27, 2005·Methods in Molecular Biology·Michal Lebl, John Hachmann

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Citations

Jun 7, 2011·Amino Acids·Xiaoyuan Chen
Jul 25, 2012·AJR. American Journal of Roentgenology·Hossein Jadvar
Jan 7, 2014·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Yuping XuYongjun Yan
Apr 25, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Brian J McParlandJens Sørensen
Sep 24, 2011·Expert Opinion on Biological Therapy·Glenn F King
Jan 31, 2016·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·V O ZambelliY Cury
Dec 4, 2012·Nuclear Medicine and Biology·Liyang CuiFan Wang
Sep 21, 2010·Advanced Drug Delivery Reviews·Kai Chen, Peter S Conti
May 4, 2011·The Prostate·Mary A HallEva M Sevick-Muraca
Dec 1, 2011·The Prostate·Susanne LütjePeter F A Mulders
Apr 15, 2014·Contrast Media & Molecular Imaging·Donghui PanMin Yang
Aug 20, 2015·Contrast Media & Molecular Imaging·Chen ZhuMin Yang
Dec 7, 2011·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Michael M Graham
Apr 27, 2012·Physiological Reviews·Michelle L James, Sanjiv S Gambhir
Jan 18, 2017·Diagnostic Pathology·Tao TangShiwu Zhang
May 21, 2019·Clinical Nuclear Medicine·Mark S ManganaroMatthew S Manganaro
Apr 30, 2021·Expert Opinion on Drug Discovery·Taylor B Smallwood, Richard J Clark
Mar 27, 2021·Physics in Medicine and Biology·Abhijit J Chaudhari, Ramsey D Badawi
Jan 15, 2011·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Michael HonerSandra Borkowski
Aug 24, 2011·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Damaris KukukBernd J Pichler
Oct 22, 2021·Journal of Medicinal Chemistry·Justin J BaileyFrank Wuest

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