PMID: 8600958Mar 1, 1996Paper

Positron emission tomography in the diagnosis and staging of urinary bladder cancer

Acta Radiologica
H AhlströmS Nilsson

Abstract

Evaluation of positron emission tomography (PET) using (18)fl 18F-2-fluoro-2-deoxy-D-glucose (18FDG) and L-methyl-11C-methionine in the diagnosis and staging of urinary bladder carcinoma. Twenty-three patients with biopsy-proven urinary bladder carcinoma were examined with PET after intravenous injection of 11C-methionine; 2 were also examined with 18FDG. The results from the PET investigations were compared with CT or MR findings and TNM classification before and after treatment. The urinary excretion of 18FDG prevented distinction of the primary tumour from the surrounding tracer. With 11C-methionine it was possible to detect 18/23 primary tumours. A trend was seen, suggesting that the higher the uptake values of 11C-methionine in the tumour, the greater the tumour stage. It is possible to visualize urinary bladder tumours larger than 1 cm in diameter with PET using (11)C-methionine, but the value of the method in the staging of the lesions is not superior to conventional methods.

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Citations

Oct 23, 2012·European Urology·Ashish M KamatUNKNOWN International Consultation on Urologic Disease-European Association of Urology Consultation on Bladder Cancer 2012
Apr 22, 2011·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·N BoujelbeneA Zouhair
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Oct 19, 2004·Radiologic Clinics of North America·Rakesh KumarAbass Alavi
Dec 17, 2005·Seminars in Nuclear Medicine·Suman Jana, M Donald Blaufox
Oct 3, 2015·Urologic Oncology·Soroush Rais-BahramiJeffrey W Nix
Jun 24, 2015·PET Clinics·Kirsten Bouchelouche, Peter L Choyke
Jun 12, 2012·Seminars in Nuclear Medicine·Sze Ting LeeAndrew M Scott
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Jul 9, 2013·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Yan ZhaoNagara Tamaki

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