Positron-emission tomography with fluorine-18-fluoro-2-deoxy-D-glucose for gallbladder cancer diagnosis

American Journal of Surgery
Antonio Rodríguez-FernándezCarlos Ramos-Font

Abstract

Recent advances in hepatobiliary surgery have underscored the need for presurgical diagnosis of gallbladder cancer. Frequently, clinical presentation, biochemical analysis, and structural ultrasound or computed axial tomography images do not enable definitive differentiation of cholecystitis or cholethiasis from gallbladder cancer. The aim of this study was to evaluate the role of fludeoxy glucose-positron-emission tomography (FDG-PET) in establishing the benign or malignant nature of gallbladder lesions. A case series of 16 patients with clinical symptoms suggestive of biliary colic or chronic cholecystitis and with inconclusive ultrasound and/or computed axial tomography findings for presence of gallbladder cancer were studied by FDG-PET. FDG-PET showed a sensitivity of 0.80, a specificity of 0.82, and positive and negative predictive values of 0.67 and 0.90, respectively. There was 1 false- negative result in 1 patient with mucinous adenocarcinoma and 2 false-positive results in 1 patient with tuberculoid granulomatous reaction and 1 patient with polypoid lesion with adenomyomatosis. FDG-PET may be of utility to establish the diagnosis of gallbladder cancer in patients with nonspecific clinical and imaging findings.

References

May 1, 1991·World Journal of Surgery·K SumiyoshiF Nakayama
Mar 27, 1998·American Journal of Surgery·H ShinkaiT Muto
Sep 10, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S KeidingJ F Dahlerup
Mar 22, 2001·Radiographics : a Review Publication of the Radiological Society of North America, Inc·J A Cooper
Mar 29, 2001·Chemotherapy·E A Kouroumalis
May 9, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R KlugeF Berr
May 12, 2001·Clinical Positron Imaging : Official Journal of the Institute for Clinical P.E.T·T KohH Yamagishi
Nov 17, 2001·Nuclear Medicine Communications·A Fritscher-RavensM Clausen
Jun 20, 2002·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·F De WinterR A Dierckx
Aug 13, 2002·European Journal of Nuclear Medicine and Molecular Imaging·Takashi KatoNagara Tamaki
Nov 16, 2002·American Journal of Surgery·Tomoharu TanakaArimichi Takabayashi

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Citations

Mar 28, 2007·Annals of Nuclear Medicine·Ai OeSusumu Shiomi
Dec 30, 2006·European Journal of Nuclear Medicine and Molecular Imaging·Jose Manuel Llamas-ElviraAntonio Ferrón-Orihuela
Oct 16, 2010·Journal of Gastrointestinal Cancer·Keiichi SuzukiYusuke Kumamoto
Jun 21, 2007·AJR. American Journal of Roentgenology·Pierre D MaldjianYiyan Liu
Jul 26, 2011·AJR. American Journal of Roentgenology·Ari SacksRathan M Subramaniam
Jan 15, 2014·Abdominal Imaging·E Rang SongEun Jung Cha
Apr 25, 2012·Abdominal Imaging·Anna Maria De GaetanoLorenzo Bonomo
Feb 6, 2016·Journal of Surgical Oncology·Mahesh GoelShailesh V Shrikhande
Apr 3, 2012·American Journal of Surgery·Billy Y LanLinda L Wong
Jul 26, 2013·Insights Into Imaging·Raneem AlbazazAndrew F Scarsbrook
Jun 5, 2014·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Universe LeungYuman Fong
Dec 18, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Parul J ShuklaVenkatesh Rangarajan
Sep 3, 2013·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Matthew David HaleGiles J Toogood
May 19, 2010·Gastroenterology Clinics of North America·Shiva Jayaraman, William R Jarnagin
Apr 1, 2008·PET Clinics·Mehmet Ertuk, Annick D Van den Abbeele
Dec 2, 2008·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Carmel G CroninMichael A Blake
Jun 17, 2008·Gastroentérologie Clinique Et Biologique·J-M RegimbeauT Yzet
Oct 30, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·G Miller, W R Jarnagin
Nov 14, 2007·Nuclear Medicine and Biology·Yuji MurataHitoshi Shibuya
Jun 15, 2007·Surgical Oncology Clinics of North America·George MillerMichael D'Angelica
Oct 30, 2013·Journal of Surgical Oncology·Carlos Ramos-FontJose Manuel Llamas-Elvira
Mar 29, 2016·The Surgical Clinics of North America·Motaz Qadan, T Peter Kingham
Mar 11, 2005·Expert Opinion on Pharmacotherapy·Gregory D Leonard, Eileen M O'Reilly
Jul 2, 2011·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Junji UedaEiji Uchida
Mar 15, 2015·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Mathieu GauthéUNKNOWN Fédération Francophone de Cancérologie Digestive (FFCD)
May 26, 2006·Journal of Surgical Oncology·Antonio Rodríguez-FernándezPablo Lardelli-Claret
Dec 24, 2005·Clinical Nuclear Medicine·Mary T Kitazono, Patrick M Colletti
Oct 31, 2006·World Journal of Gastroenterology : WJG·J M RamiaJ A Ferron
Dec 6, 2017·Indian Journal of Surgical Oncology·Rajaguru KishoreShailendra Lalwani
Nov 7, 2018·Journal of Gastrointestinal Cancer·Vikas GuptaK Vaiphei
Nov 3, 2015·World Journal of Gastroenterology : WJG·Salvatore AnnunziataGiorgio Treglia
Jan 3, 2021·Abdominal Radiology·Dhakshinamoorthy GaneshanCatherine Devine
Apr 6, 2012·Clinical Nuclear Medicine·Rakesh KumarArun Malhotra
Nov 13, 2020·World Journal of Gastroenterology : WJG·Pankaj GuptaManavjit Singh Sandhu
Feb 9, 2012·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Jaehoon LeeChun K Kim

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