Possibilities and limitations of magnetic source imaging of methohexital-induced epileptiform patterns in temporal lobe epilepsy patients

Electroencephalography and Clinical Neurophysiology
A BrockhausC E Elger

Abstract

The usefulness of MEG-based techniques in lateralizing and localizing the epileptogenic area was investigated in the present study. Spontaneous and methohexital-induced spikes were studied in a group of 15 patients with temporomesial epilepsy using a 37-channel neuromagnetometer. The accuracy of the magnetic source imaging was compared to the results of electrocorticographic (ECoG) recordings. Differences of drug-induced spike densities in the MEG recordings between both sides confirmed a similar lateralizing power of the MEG and ECoG recordings. Source location analyses based on a moving dipole model resp. a rotating dipole model were performed using a spherical head model. After subdivision of the volume of each patient's head, 8 cm3 cubicles containing at least 3 source locations were projected onto the individual MRI scan and resulted in source locations within or close to the presurgically defined primary epileptogenic area only in 3 of the 15 patients. Spike induction by methohexital has the advantage of shortening the recording period as compared to recordings of interictal epileptiform discharges. However, the correlation analyses of spike densities from MEG and ECoG recordings and the source location analyses from MEG ...Continue Reading

References

Aug 1, 1992·IEEE Transactions on Bio-medical Engineering·J C de MunckF H Lopes da Silva
Jan 1, 1991·Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics·B Lütkenhöner
Jan 1, 1991·Acta Oto-laryngologica. Supplementum·B LütkenhönerC Pantev
Apr 1, 1991·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
Dec 1, 1990·Annals of Neurology·D CohenD L Schomer
Jan 1, 1986·Electroencephalography and Clinical Neurophysiology·P L Nunez
Mar 1, 1986·Electroencephalography and Clinical Neurophysiology·M R SperlingP H Crandall
Jan 1, 1989·Journal of Neurology·J AaslyB Zetterlund
Oct 1, 1971·Journal of Neurology, Neurosurgery, and Psychiatry·J Gumpert, R Paul
Apr 1, 1980·Electroencephalography and Clinical Neurophysiology·C E Elger, E J Speckmann
Dec 1, 1982·Anesthesia and Analgesia·E W FordW W Whisler
Sep 1, 1994·Electroencephalography and Clinical Neurophysiology·N NakasatoW W Sutherling
Feb 1, 1995·Electroencephalography and Clinical Neurophysiology·S GharibR L Rogers
Oct 1, 1994·IEEE Transactions on Bio-medical Engineering·E MenninghausS L Gonzalez
Jan 1, 1994·Neurophysiologie clinique = Clinical neurophysiology·M Scherg, J S Ebersole
Apr 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·G AlarconC E Polkey
Jul 1, 1993·Epilepsy Research·R M Dasheiff, W A Kofke
Sep 1, 1993·IEEE Transactions on Bio-medical Engineering·A I AhonenV A Vilkman
Sep 1, 1993·IEEE Transactions on Bio-medical Engineering·Y Ogura, K Sekihara
Jan 1, 1993·IEEE Transactions on Bio-medical Engineering·B N Cuffin
Feb 1, 1952·Electroencephalography and Clinical Neurophysiology·G PAMPIGLIONE

❮ Previous
Next ❯

Citations

Aug 28, 2002·Medical & Biological Engineering & Computing·A KandoriK Tsukada
Apr 7, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Christoph Baumgartner
Sep 19, 1998·Electroencephalography and Clinical Neurophysiology·V DiekmannK H Wollinsky
Apr 7, 2000·Brain Research. Brain Research Reviews·P C Ragazzo, A S Galanopoulou
Apr 16, 2002·Epilepsia·Masaki IwasakiTakashi Yoshimoto
Jun 1, 2000·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·C BaumgartnerL Deecke
Oct 29, 2004·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Alberto FernándezTomás Ortiz
Oct 29, 2004·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Martine GavaretPatrick Chauvel
Apr 18, 2008·Neuro-Chirurgie·M GavaretP Chauvel
Jun 14, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Lorena Vega-ZelayaGuillermo J Ortega
Mar 29, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·B KettenmannH Stefan
Jan 1, 2010·Epilepsy Research and Treatment·Ivan Herrera-PecoJesús Pastor
Jul 26, 2003·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Gregory L Barkley, Christoph Baumgartner
Feb 23, 2013·Anesthesia and Analgesia·Jason ChuiPirjo Manninen

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
Christoph BaumgartnerLüder Deecke
The Journal of Neuropsychiatry and Clinical Neurosciences
Kenjiro FukaoKazuichi Yagi
© 2021 Meta ULC. All rights reserved