PMID: 6401910Feb 1, 1983Paper

Possible biotin deficiency in adults receiving long-term total parenteral nutrition

The American Journal of Clinical Nutrition
S M Innis, D B Allardyce

Abstract

Two adult patients receiving total parenteral nutrition on a long-term home basis presented with severe loss of hair. Both patients had extensive gut resection, consumed no biotin orally and received no biotin parenterally. Supplementation with Berroca-C, one ampule containing 200 micrograms biotin per day resulted in gradual regrowth of healthy hair. The patients now receive a parenteral solution containing biotin and have shown no recurrence of alopecia. It is suggested that biotin deficiency can occur in the adult when no preformed biotin is provided to the body and the contribution of this vitamin from intestinal microbial biosynthesis is compromised.

Citations

Jul 1, 1987·Drug Intelligence & Clinical Pharmacy·J M Mirtallo, T Oh
Jan 1, 1985·Annals of the New York Academy of Sciences·D M MockL Sweetman
Sep 9, 2010·Current Opinion in Clinical Nutrition and Metabolic Care·Suzie Daniells, Gil Hardy
Jan 14, 2012·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Barry Wolf
Aug 9, 2020·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Ozan Şen, Ahmet Gökhan Türkçapar
Jan 1, 1985·Annals of the New York Academy of Sciences·J P Bonjour
Nov 13, 2004·The Journal of Nutritional Biochemistry·J Zempleni, D M Mock

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