PMID: 1202417Dec 1, 1975Paper

Possible immunological damage to the tegument of Hymenolepis diminuta in mice and rats

Parasitology
A D Befus, L T Threadgold

Abstract

Opaque or darkened areas (DA) of variable size and position occur on Hymenolepis diminuta in mice and rats. In mice DA normally first appear in the neck region of the worm but subsequently they appear elsewhere and increase in number until destrobilation or worm expulsion. The posterior of destrobilated worms is often darkened. In the more immunogenic infections with six cysticercoids there are more DA per worm than in infections with one cysticercoid. DA are areas of the tegument with a homogeneous increase in electron density; abnormal mitochondria; reduced granular endoplasmic reticulum, Golgi complexes and discoidal secretory bodies; and accumulation of lipid droplets. DA disappear from worms maintained for up to 4 h in Hanks' balanced salt solution and can be induced by mechanical damage to the worms. As the numbers of DA increase with the duration and intensity of infection and have similarities with types of cell injury, they are probably sites of worm pathology induced by host immunity.

References

Apr 1, 1975·Experimental Parasitology·R D Lumsden
Mar 1, 1972·Annals of Internal Medicine·J Churg, E Grishman
Aug 1, 1974·Parasitology·C A Hopkins, H E Stallard
Jun 1, 1972·International Journal for Parasitology·B E SandersonR F Phillipson
Apr 1, 1973·Parasitology·C A HopkinsH Stallard
Aug 1, 1970·Parasitology·D J Hockley, S R Smithers
Oct 1, 1970·Experimental Parasitology·L T Threadgold, C P Read
Jan 1, 1966·Proceedings of the Society for Experimental Biology and Medicine·S Levine, E J Wenk

❮ Previous
Next ❯

Citations

Feb 1, 1991·International Journal for Parasitology·C A Hopkins, J Andreassen
Jul 1, 1997·International Journal for Parasitology·C PalmasM Conchedda
Dec 1, 1989·Parasitology·J Andreassen, D Hoole
Feb 1, 1987·International Journal for Parasitology·M D McCaigue, D W Halton
Aug 1, 1982·International Journal for Parasitology·C A Hopkins, I F Barr
Aug 1, 1981·International Journal for Parasitology·T FurukawaT Miyazato
Feb 1, 1978·International Journal for Parasitology·A E SiebertJ E Simmons
Apr 1, 1980·Experimental Parasitology·A Ito
Apr 1, 1978·Experimental Parasitology·C A HopkinsL T Threadgold
Aug 1, 1986·Experimental Parasitology·M D McCaigueC A Hopkins

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.