PMID: 8448725Feb 1, 1993Paper

Possible interaction between fluoxetine and pimozide causing sinus bradycardia

Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie
I AhmedR I Shader

Abstract

Fluoxetine has been reported to have interactions with antipsychotics and other antidepressants with symptoms of toxicity of these drugs. We report a case of a possible interaction with pimozide which led to a potentially life threatening bradycardia. Careful monitoring should be done when these two drugs are prescribed at the same time, especially in the elderly and in patients with cardiac disease.

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