Possible intermediary role of ghrelin in seborrhea

Medical Hypotheses
Zareie ElhamSadeghpour Omid

Abstract

Seborrhea, or oily skin, is a very common condition, especially among young people, caused by the increased secretion of sebum by sebaceous glands in the skin. Based on today's knowledge, a regulatory role of various hormones especially androgens is considered for sebaceous gland secretion; but despite significant evidences emphasis on the effects of the gastrointestinal disorders on coetaneous manifestations, the role of gastrointestinal problems in sebum secretion has not been emphasized yet. This study aimed to explain hormonal changes occurring in gastroesophageal reflux disease which may cause changes in sebaceous gland secretion so that, by explaining these communication mechanisms, common investigations between gastroenterology and dermatology can be performed to evaluate the accuracy of this hypothesis.

References

Feb 5, 2003·Dermatology : International Journal for Clinical and Investigative Dermatology·Christos C Zouboulis, Jaime Piquero-Martin
Oct 26, 2007·The Journal of Investigative Dermatology·Il HongMi-Ock Lee
May 14, 2008·Experimental Dermatology·Christos C ZouboulisAnja Thielitz
Mar 13, 2010·Dermato-endocrinology·Wen-Chieh Chen, Christos C Zouboulis
Mar 1, 2012·PloS One·Agustina CabralMario Perello
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Aug 21, 2013·Journal of Obesity·Michael LaffinShahzeer Karmali

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Citations

Jun 23, 2020·International Journal of Endocrinology·Yonas AkaluBirhanu Ayelign

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