PMID: 7026993Aug 1, 1981Paper

Possible involvement of endorphin withdrawal or imbalance in specific premenstrual syndromes and postpartum depression

Medical Hypotheses
U Halbreich, J Endicott

Abstract

Premenstrual and postpartum dysphoric changes are very prevalent. However, their etiology is still obscure. The authors hypothesize that changes in levels of endorphins may be involved in the pathophysiology of these changes. Studies of various endorphins indicate a possible relationship between levels of endorphins and depressive symptoms. In addition, some studies of naloxone and naltrexone suggest a relationship between a blockage in the action of endorphins and the development of a syndrome of dysphoric symptoms similar to the depressive features manifested premenstrually and postpartum by many women and frequently seen in some depressed outpatients. There is also some evidence that there may be a relationship between elevated levels of endorphins and other subtypes of depressive syndromes. Endorphins and estrogen levels have been shown to covary. During the postpartum and the premenstrual period, levels of both change rapidly and substantially. Therefore the link between changes in levels of endorphins and the dysphoric changes during the periods in focus is supported from three complementary directions: (1) the characteristic psychiatric symptomatology, (2) the reported hormonal changes, and (3) the possible involvement o...Continue Reading

References

Jan 1, 1976·Progress in Neurobiology·E Eidelberg
Apr 1, 1978·Psychoneuroendocrinology·A E Boyd, S Reichlin
Jan 1, 1979·Schizophrenia Bulletin·J VolavkaY H Ehrlich
Jan 1, 1979·Schizophrenia Bulletin·G C DavisW E Bunney
Jul 30, 1979·Life Sciences·A J KastinD H Coy
May 22, 1976·Lancet·L J Benedek-Jaszmann, M D Hearn-Sturtevant
Sep 25, 1976·Lancet·U HalbreichR Bornstein
Oct 28, 1976·Nature·A El-SobkyP D Wall
Apr 7, 1977·Nature·J D Belluzzi, L Stein
Aug 25, 1977·Nature·H PollardJ C Schwartz
Oct 1, 1977·Archives of General Psychiatry·A Goldstein, R W Hansteen
Nov 24, 1977·Nature·L Grandison, A Guidotti
Oct 1, 1977·Psychoneuroendocrinology·M Steiner, B J Carroll
Jun 1, 1978·The American Journal of Psychiatry·S H Snyder
Jul 1, 1978·Archives of General Psychiatry·K VerebeyD Clouet
Oct 1, 1978·Psychoneuroendocrinology·J H MendelsonN K Mello
Jun 1, 1979·The American Journal of Psychiatry·H LehmannN S Kline
Nov 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·J RossierR Guillemin
Jul 1, 1979·Psychiatry Research·A PfefferbaumC H Li
Mar 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·P Grevert, A Goldstein
May 1, 1977·British Journal of Obstetrics and Gynaecology·A N AndersenJ Nielsen
Apr 27, 1978·Nature·J D LevineH L Fields
Nov 1, 1979·Acta Psychiatrica Scandinavica·M Steiner
Feb 1, 1978·Acta Psychiatrica Scandinavica·L H LindströmL Terenius
May 1, 1978·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·P D PezallaM Chrétien
Aug 21, 1978·Life Sciences·B P QuarantottiG L Gessa
Sep 4, 1978·Life Sciences·G R van Loon, C Kim
Sep 4, 1978·Life Sciences·G R van Loon, E B De Souza
Sep 1, 1977·Archives of General Psychiatry·N S KlineT Cooper
Jan 1, 1976·Journal of Psychosomatic Research·P Sheldrake, M Cormack
Jan 1, 1971·Journal of Comparative and Physiological Psychology·J A Harvey, C E Lints

❮ Previous
Next ❯

Citations

Jun 1, 1984·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·A J GianniniR H Loiselle
Mar 1, 1994·Progress in Neuro-psychopharmacology & Biological Psychiatry·A J GianniniD J Folts
Jan 1, 1985·Psychoneuroendocrinology·U Halbreich, J Endicott
Jan 1, 1990·Psychoneuroendocrinology·F FacchinettiA R Genazzani
Aug 1, 1991·The Journal of Steroid Biochemistry and Molecular Biology·V Dhar, B E Murphy
Aug 2, 2003·Psychoneuroendocrinology·Uriel Halbreich
Jul 2, 2002·Health Psychology : Official Journal of the Division of Health Psychology, American Psychological Association·Patricia A StranevaSusan S Girdler
Jul 1, 1983·Journal of Psychoactive Drugs·J Harrison
Oct 30, 2008·Journal of Addictive Diseases·Peter L Tenore
Apr 18, 2009·Harvard Review of Psychiatry·Joanne CunninghamElias Eriksson
Aug 9, 2006·Medical Hypotheses·Péter Apari, Lajos Rózsa
Jan 4, 2006·Hormones and Behavior·Anita N DiMeo, Ruth I Wood
Jan 2, 2004·Journal of Psychosomatic Obstetrics and Gynaecology·S Gale, B L Harlow
Mar 2, 2013·The International Journal of Neuropsychopharmacology·Ana C Andreazza, L Trevor Young
Jan 1, 1993·International Journal of Psychiatry in Medicine·U Halbreich, H Tworek
Jan 1, 1990·International Journal of Psychiatry in Medicine·A J GianniniC E Turner
Aug 1, 1988·Psychological Reports·L A FuttermanM E Quigley
Jan 1, 1987·British Journal of Obstetrics and Gynaecology·A TulenheimoK Salminen
Mar 1, 1985·British Journal of Obstetrics and Gynaecology·J F WattsG Holder
Jan 1, 1981·Nursing Forum·K M Kerfoot, K C Buckwalter
Aug 16, 2003·Endocrine Reviews·Ze'ev HochbergGeorge P Chrousos
Jan 18, 2007·Journal of Psychosomatic Obstetrics and Gynaecology·G Di Giulio, E D Reissing
Sep 14, 2002·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·U H WinklerC Oberhoff
Mar 1, 1985·Clinical Endocrinology·J Bancroft, T Bäckström
Jun 1, 1984·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·D S Goldbloom

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Psychiatry in Medicine
A J GianniniC E Turner
British Journal of Obstetrics and Gynaecology
A TulenheimoK Salminen
© 2021 Meta ULC. All rights reserved