Possible Role of Environmental Factors in the Development of Food Allergies

Clinical Reviews in Allergy & Immunology
Jodi ShrobaCharles Barnes

Abstract

The development of food allergies is thought to involve multiple factors, and it is unclear which conveys the most risk regarding this process. Since food allergy is a chronic disease without a cure at this time, understanding its development could provide an avenue for preventive practices and development of a curative treatment. Both historical and current data implicate maternal factors, genetics, and environmental exposures as major risk factors in the development of food allergy. An immature gut of the infant has been hypothesized as a possible route of sensitization. Breastfeeding until at least 6 months of age has been shown to have protective factors for the newborn and may possibly improve gut permeability. Newer studies such as the LEAP and EAT investigations also looked at early exposure and prevention of food allergies; their long-term results are critical in understanding early introduction and tolerance. Cutaneous exposure, oral exposure, and food protein exposure in house dust with their relation to the food allergy course are also a path of interest. Current research has shown sensitization can occur through impaired skin such as those with eczema and a filaggrin mutation. Tropomyosin and alpha-gal also are rela...Continue Reading

References

Mar 1, 1992·The Journal of Allergy and Clinical Immunology·K Fälth-Magnusson, N I Kjellman
Jan 1, 1989·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·G HattevigN I Kjellman
Jul 20, 1999·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·L FrankP C Potter
Dec 14, 2001·The Journal of Allergy and Clinical Immunology·S H Sicherer
Apr 20, 2002·Science·Maria YazdanbakhshRonald van Ree
Jun 5, 2002·Current Opinion in Allergy and Clinical Immunology·Scott H Sicherer
Jan 11, 2007·Pediatric Research·David S Newburg, W Allan Walker
Nov 20, 2008·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H-J TsaiX Wang
Oct 23, 2009·Allergology International : Official Journal of the Japanese Society of Allergology·Yasuto Kondo, Atsuo Urisu
Jan 22, 2010·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Takashi KusunokiTatsutoshi Nakahata
May 1, 2010·Current Opinion in Allergy and Clinical Immunology·Constance Helen Katelaris
Jun 23, 2010·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Gordon SussmanDavid Sussman
Mar 1, 2011·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Manuel BoqueteJerónimo Carnés
Aug 30, 2011·The Journal of Allergy and Clinical Immunology·Julie WangHugh A Sampson
Apr 3, 2012·The Journal of Allergy and Clinical Immunology·Gideon Lack
Oct 12, 2012·Current Allergy and Asthma Reports·Scott P Commins, Thomas A E Platts-Mills
Nov 24, 2012·The Journal of Allergy and Clinical Immunology·George Du ToitUNKNOWN Learning Early About Peanut Allergy (LEAP) Study Team
Feb 15, 2013·Allergy and Asthma Proceedings·Rodney M Johnson, Charles S Barnes
Apr 24, 2013·The Journal of Allergy and Clinical Immunology·Helen A BroughGideon Lack
Apr 24, 2013·The Journal of Allergy and Clinical Immunology·Helen A BroughGideon Lack
Oct 30, 2013·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K M JärvinenC Berin
Jan 7, 2014·The Journal of Allergy and Clinical Immunology·Scott H Sicherer, Hugh A Sampson
Aug 19, 2014·The Journal of Allergy and Clinical Immunology·Peter M Elias, Joan S Wakefield
Sep 14, 2014·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Alfredo J LucendoJosé M Tenias
Dec 3, 2014·The Journal of Allergy and Clinical Immunology·Helen A BroughGideon Lack
Feb 24, 2015·The New England Journal of Medicine·George Du ToitUNKNOWN LEAP Study Team
Jul 2, 2015·Current Allergy and Asthma Reports·Thomas A E Platts-MillsScott P Commins
Jul 4, 2015·World Journal of Methodology·Florin-Dan Popescu
Jan 8, 2016·Allergy, Asthma & Immunology Research·Lydia WongBee Wah Lee
Mar 5, 2016·The New England Journal of Medicine·George Du ToitUNKNOWN Immune Tolerance Network LEAP-On Study Team
Mar 5, 2016·The New England Journal of Medicine·Michael R PerkinUNKNOWN EAT Study Team
Apr 10, 2016·The Journal of Allergy and Clinical Immunology·George du ToitGideon Lack
May 2, 2016·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·M Angeles López-MatasJerónimo Carnés
Oct 30, 2016·Current Opinion in Immunology·David J MartinoSusan L Prescott
Jul 17, 2016·The Journal of Allergy and Clinical Immunology. in Practice·Ruchi S GuptaBridget Smith
Aug 16, 2016·Current Opinion in Allergy and Clinical Immunology·Daniel Munblit, Valérie Verhasselt
Jan 4, 2017·The Journal of Allergy and Clinical Immunology. in Practice·David A HillJonathan M Spergel
Apr 27, 2017·Allergy and Asthma Proceedings·Jodi ShrobaChristina Ciaccio
May 18, 2017·Journal of Paediatrics and Child Health·Anna ChmielewskaHania Szajewska

❮ Previous
Next ❯

Citations

Feb 27, 2020·International Journal of Molecular Sciences·Massimo De MartinisLia Ginaldi
Apr 3, 2020·Archivum Immunologiae Et Therapiae Experimentalis·Massimo De MartinisLia Ginaldi
Jun 1, 2021·Current Allergy and Asthma Reports·Laura De MarchiGianni Zoccatelli
Oct 11, 2021·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Abigail LangRajesh Kumar

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Related Papers

Nestlé Nutrition Workshop Series. Paediatric Programme
Gideon Lack, Martin Penagos
Immunology and Allergy Clinics of North America
Kirsi M Järvinen, David M Fleischer
American Family Physician
Barbara P Yawn, Matthew J Fenton
Royal Society of Health Journal
A W Frankland
Der Internist
Stephan Bischoff, M P Manns
© 2022 Meta ULC. All rights reserved