PMID: 9427959Jan 15, 1998Paper

Possible role of transforming growth factor-beta in relapsing-remitting multiple sclerosis

Neurological Research
P B CarrieriO Perrella

Abstract

Cerebrospinal fluid (CSF) and serum levels of transforming growth factor (TGF)-beta and soluble intercellular adhesion molecule-1 (sICAM-1) were evaluated in ten patients with definite multiple sclerosis (MS) of the relapsing-remitting type. CSF TGF-beta levels of MS patients in remission were significantly (p < 0.01) higher than of MS patients in active phase, and there was a significant inverse correlation (p < 0.05) between TGF-beta and slCAM-1 levels in the CSF of patients in both remitting and relapsing type. This is consistent with a possible down-regulation of TGF-beta on ICAM-1 expression and suggests a possible synthesis in the central nervous system of TGF-beta.

Citations

Dec 1, 2017·Acta Biochimica Et Biophysica Sinica·Risa Kashima, Akiko Hata
Sep 29, 2004·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Hans M SchrijverBernard M J Uitdehaag
Mar 12, 2003·The Journal of Clinical Endocrinology and Metabolism·A OlivieriM Boirivant
Sep 4, 2012·International Journal of Molecular Sciences·Arpád DobolyiGábor Lovas
Aug 16, 2019·Inflammation Research : Official Journal of the European Histamine Research Society ... [et Al.]·Tamires FlauzinoEdna Maria Vissoci Reiche
Mar 23, 2006·Neurological Research·Oreste PerrellaPietro Carrieri
Sep 27, 2019·Molecular Biology Reports·Rahim Heidari Barchi NezhadMohammad Reza Mirzaei
Jun 15, 2019·Cells·Frances K NallyClaire E McCoy

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.