PMID: 2116104Jan 1, 1990Paper

Possible typhus-group infection in New York State: presentation of four suspect cases

Annals of the New York Academy of Sciences
D J WhiteN Ionascu

Abstract

Epidemiologic investigations were recently conducted on four cases which were reported in New York State in 1986 and 1987, three of which were within one family. These included hospital chart reviews, case or family interviews, animal trappings, and ectoparasite surveys. Serologic tests and immunoblots were performed on blood samples obtained from these patients. All four patients had acute febrile illnesses; two required hospitalization and one died. Microimmunofluorescence test results using Rickettsia typhi and R. prowazekii antigens showed a greater than or equal to 4-fold increase in titer with paired sera from three patients. The remaining patient had a single serum titer of 4096 with both antigens. In addition, sera from all patients reacted with R. typhi in the immunoblot test and, from the three patients for whom sera were available, also with R. prowazekii. Results suggest that the four patients were exposed to the typhus-group rickettsiae or to an organism which shares a common epitope(s).

References

Jun 1, 1975·Infection and Immunity·R L AnackerW D Bickel
Jan 1, 1976·Journal of Clinical Microbiology·R N PhilipW Burgdorfer
Jul 1, 1989·Archives of Internal Medicine·C C LinnemannE D Peterson
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Jan 1, 1981·Journal of Clinical Microbiology·K E HechemyS J Sasowski
Aug 1, 1980·Journal of Clinical Microbiology·K E HechemyE E Michaelson

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Citations

Dec 1, 1992·International Journal of Dermatology·A S Boyd, K H Neldner
Apr 3, 2014·Vector Borne and Zoonotic Diseases·Melissa A PrusinskiDennis J White
Apr 1, 1994·Journal of Clinical Microbiology·M E SchrieferA F Azad

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