PMID: 192251Mar 1, 1977Paper

Possible utilization of extracorporeal hemoperfusion in the treatment of coronary artery disease. A hypothesis and proposal for animal studies

Atherosclerosis
M Strahilevitz

Abstract

It is proposed that in vivo immunoadsorption may be utilized in the treatment of coronary artery disease. The proposed method is based on binding of low density lipoproteins and cholesterol to antibodies directed against low density lipoproteins which are bound to a matrix in an extracorporeal hemoperfusion column. The various observations that suggest the hypothesis are presented. The feasibility of the proposed method and some of the problems that may be encountered in its utilization are discussed. The method should be evaluated in animal studies prior to consideration of clinical trials in patients.

References

May 1, 1974·Atherosclerosis·R N Poston, D F Davies
Dec 1, 1974·Annals of Internal Medicine·W B DunkmanJ C Shelburne
Jan 1, 1971·Annals of Internal Medicine·W B KannelP M McNamara
Apr 15, 1971·The New England Journal of Medicine·J L RosenbaumC Boreyko
Oct 1, 1955·Proceedings of the Society for Experimental Biology and Medicine·S B STANDERFER, P HANDLER
Jan 1, 1957·The Journal of Experimental Medicine·F ALADJEMM LIEBERMAN

Citations

Jul 25, 1992·Lancet·M LaaksoK Pyörälä

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