Post-anesthesia recovery after infusion of propofol with remifentanil or alfentanil or fentanyl in morbidly obese patients

Obesity Surgery
Tomasz M GaszynskiWojciech P Gaszynski

Abstract

The type of opioid used during general anesthesia in the morbidly obese influences recovery and the postoperative period. In a randomized clinical trial, the postoperative recovery profile and early period after general anesthesia with remifentanil, fentanyl and alfentanil were compared in morbidly obese patients. 60 morbidly obese patients with BMI >35 kg/m(2) (mean 43.31) undergoing open Roux-en-y gastric bypass were randomly divided into 3 groups: remifentanil (R), fentanyl (F), and alfentanil (A). Dosage of opioids was based on ideal body weight (IBW): fentanyl 5 mcg/kg for intubation followed by infusion of 0.025-0.05 mcg/kg/min; alfentanil 15 mcg/kg initially, then 1.0-1.5 mcg kg/min; and remifentanil 1 mcg/kg followed by infusion of 0.25-1.5 mcg/kg/min. Anesthesia was induced with infusion of propofol and oxygen with N(2)O (1:1). After anesthesia, the duration to response to verbal command, spontaneous respiration, adequate respiration, and safe extubation were recorded. The incidence of postoperative nausea and vomiting were recorded. Using verbal scale for evaluation of postoperative pain, the early postoperative analgesia requirements were assessed. Demographic profiles and duration of procedure did not differ between...Continue Reading

Citations

Mar 16, 2013·Saudi Journal of Anaesthesia·Masood EntezariaslKhatereh Isazadehfar
Dec 19, 2013·Saudi Journal of Anaesthesia·Mohamed Ahmed MansourMohammed Geddawy
Oct 13, 2009·Acta Anaesthesiologica Scandinavica·Kevin D Johnston
Oct 25, 2016·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Adele Sandra BudianskyNaveen Eipe
Feb 6, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·James Norman, Kelly Aronson
Nov 10, 2007·Anaesthesia·R KomatsuC C Apfel
Nov 20, 2010·European Journal of Anaesthesiology·Javad BidgoliPhilippe J Van der Linden
Sep 13, 2018·Journal of Anesthesia·Tatsunori WatanabeHiroshi Baba
Jul 1, 2019·Drugs·Imane Belcaid, Naveen Eipe

Related Concepts

Remifentanil monohydrochloride
Opioids
General Anesthesia
Sublimaze
Visual Analog Pain Scale
Pain, Postoperative
Piperidines
Postoperative Period
Roux-en-Y Gastrojejunostomy
Propofol Rovi

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