Post-hematopoietic stem cell transplant immunization practices in the Pediatric Blood and Marrow Transplant Consortium

Pediatric Blood & Cancer
Michelle P HudspethDominic Ragucci

Abstract

A survey of National Marrow Donor Program transplant centers in 1995 demonstrated a wide range of immunization practices in post-hematopoietic stem cell transplant (HSCT) recipients, which led to the 2000 Centers for Disease Control and Prevention (CDC) recommendations for vaccination after HSCT. We surveyed the principal investigators of the Pediatric Blood and Marrow Transplant Consortium (PBMTC) to identify immunization practice patterns after HSCT and assess compliance with the 2000 CDC guidelines. Approval was obtained from the Medical University of South Carolina Institutional Review Board. A 33 question survey using surveymonkey.com was distributed by email to principal investigators in the PBMTC. Forty-one (40%) of the 102 pediatric HSCT centers participating in the PBMTC responded. Thirty of the responding centers completed the entire survey. For individual vaccines, compliance with the CDC guidelines ranged from 22% to 93%. Less than 20% of the centers reported schedules consistent with the 2000 CDC recommendations for both allogeneic and autologous HSCT recipients. Despite the 2000 CDC guidelines, wide variation in post-HSCT immunization practices still exists. Updated guidelines have been needed, particularly to add...Continue Reading

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Citations

Nov 26, 2015·Blood Reviews·C Tsigrelis, P Ljungman
Nov 19, 2014·Transplant Infectious Disease : an Official Journal of the Transplantation Society·E J Ariza-HerediaR F Chemaly
Sep 24, 2013·Health Policy·Ashley N CoralloTherese A Stukel
Nov 9, 2017·Revista Do Instituto De Medicina Tropical De São Paulo·Paula Moreira da SilvaClarisse Martins Machado
Dec 27, 2018·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Gemma DyerIan Kerridge
Feb 19, 2020·Mayo Clinic Proceedings·Jennifer A Whitaker
Nov 20, 2012·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·Julie L LukeNorma G Cuellar

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