Post hemorrhagic hydrocephalus and neurodevelopmental outcomes in a context of neonatal intraventricular hemorrhage: an institutional experience in 122 preterm children

BMC Pediatrics
Vianney GilardSophie Curey

Abstract

Intraventricular hemorrhage (IVH) is a frequent complication in extreme and very preterm births. Despite a high risk of death and impaired neurodevelopment, the precise prognosis of infants with IVH remains unclear. The objective of this study was to evaluate the rate and predictive factors of evolution to post hemorrhagic hydrocephalus (PHH) requiring a shunt, in newborns with IVH and to report their neurodevelopmental outcomes at 2 years of age. Among all preterm newborns admitted to the department of neonatalogy at Rouen University Hospital, France between January 2000 and December 2013, 122 had an IVH and were included in the study. Newborns with grade 1 IVH according to the Papile classification were excluded. At 2-year, 18% (n = 22) of our IVH cohort required permanent cerebro spinal fluid (CSF) derivation. High IVH grade, low gestational age at birth and increased head circumference were risk factors for PHH. The rate of death of IVH was 36.9% (n = 45). The rate of cerebral palsy was 55.9% (n = 43) in the 77 surviving patients (49.4%). Risk factors for impaired neurodevelopment were high grade IVH and increased head circumference. High IVH grade was strongly correlated with death and neurodevelopmental outcome. The impac...Continue Reading

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Citations

Mar 13, 2020·Clinical Neuroradiology·Victor SchmidbauerGregor Kasprian
Aug 6, 2020·Journal of Clinical Medicine·Vianney GilardStéphane Marret
Dec 22, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Evan LutherToba Niazi
Sep 22, 2019·Epilepsia·Yi-Fang TuChao-Ching Huang
Sep 6, 2020·Epilepsy & Behavior : E&B·Francesco PisaniCarlotta Spagnoli
Nov 12, 2020·International Journal of Molecular Sciences·Isabel Atienza-NavarroMonica Garcia-Alloza
Apr 6, 2021·International Journal of Pediatrics·Walufu Ivan EgesaPatrick Kumbowi Kumbakulu
Jan 20, 2022·British Journal of Neurosurgery·L A Foster-DaviesI Jalloh

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