Post-imaging colorectal cancer or interval cancer rates after CT colonography: a systematic review and meta-analysis

The Lancet. Gastroenterology & Hepatology
Anu ObaroDavid Burling

Abstract

CT colonography is highly sensitive for colorectal cancer, but interval or post-imaging colorectal cancer rates (diagnosis of cancer after initial negative CT colonography) are unknown, as are their underlying causes. We did a systematic review and meta-analysis of post-CT colonography and post-imaging colorectal cancer rates and causes to address this gap in understanding. We systematically searched MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials. We included randomised, cohort, cross-sectional, or case-control studies published between Jan 1, 1994, and Feb 28, 2017, using CT colonography done according to international consensus standards with the aim of detecting cancer or polyps, and reporting post-imaging colorectal cancer rates or sufficient data to allow their calculation. We excluded studies in which all CT colonographies were done because of incomplete colonoscopy or if CT colonography was done with knowledge of colonoscopy findings. We contacted authors of component studies for additional data where necessary for retrospective CT colonography image review and causes for each post-imaging colorectal cancer. Two independent reviewers extracted data from the study reports. Our primary outcome was ...Continue Reading

Citations

Jun 22, 2018·The British Journal of Radiology·Anu E ObaroAndrew A Plumb
Feb 28, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A A PlumbA Thrower
Nov 13, 2019·AJR. American Journal of Roentgenology·Jeannine A RubyPerry J Pickhardt
Dec 20, 2018·Der Radiologe·T Mang
Apr 10, 2019·European Radiology·Anu E ObaroDavid N Burling
Jul 9, 2020·Cell Biochemistry and Biophysics·Zhicheng ZhaoWeidong Li
Mar 26, 2021·World Journal of Gastrointestinal Endoscopy·Jelena PopicAnna Mrzljak
Apr 18, 2021·Advances in Therapy·Natalia CalanzaniFiona M Walter
Dec 23, 2021·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Campbell MacLeodAngus J M Watson

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