Post-irradiation dietary vitamin E does not affect the development of radiation-induced lung damage in rats

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
E M WiegmanRob P Coppes

Abstract

The purpose of this study was to investigate whether application of post-irradiation vitamin E, an anti-oxidant, could prevent the development of radiation induced lung damage. Wistar rats were given vitamin E enriched or vitamin E deprived food starting from 4 weeks after 18Gy single dose irradiation of the right thorax. Neither breathing frequencies nor CT density measurements revealed differences between the groups. It is concluded that post-irradiation vitamin E does not influence radiation-induced fibrosis to the lung.

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Citations

Feb 22, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Vildan KayaAyşen Yeşim Yalçın
Nov 15, 2007·Antioxidants & Redox Signaling·Brian J Day
Feb 13, 2007·International Journal of Radiation Oncology, Biology, Physics·Thomas GuerreroElizabeth Travis
Dec 9, 2009·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K AllanG Devereux

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