Post-karyokinesis centrosome movement leaves a trail of unanswered questions

Cell Motility and the Cytoskeleton
Young Y Ou, Jerome B Rattner

Abstract

The centrosome is a complex structure composed of a large number of proteins (pericentriolar material, PCM) usually organized around a pair of centrioles (or a centriole duplex). This structure is capable of nucleating and organizing microtubules, duplication, and motility. In general, episodes of dramatic centrosome movement correlate with periods of cellular reorganization and nowhere is cellular reorganization more apparent, or more important, than in the periods before and after cell division. It is now clear that centrosome movement occurs not only prior to cell division but also at its completion, in concert with cytokinesis. The focus of this review is the newly emerging picture of centrosome activity during the post-karyokinesis period and the role that this activity might play in the transition of cells from mitosis to interphase.

References

Jun 1, 1977·The Journal of Cell Biology·J M Mullins, J J Biesele
Mar 10, 1976·Chromosoma·J B Rattner, M W Berns
Jan 1, 1992·Cell Motility and the Cytoskeleton·J B Rattner
May 1, 1973·The Journal of Cell Biology·J B Rattner, S G Phillips
Feb 1, 1968·The Journal of Cell Biology·E RobbinsA Micali
Dec 1, 1981·The Journal of Cell Biology·R Kuriyama, G G Borisy
Feb 1, 1995·Current Opinion in Cell Biology·J L Salisbury
Feb 1, 1994·Current Opinion in Cell Biology·J G Ault, C L Rieder
Jan 1, 1993·Cell Motility and the Cytoskeleton·G Mack, J B Rattner
Jan 1, 1996·Cell Motility and the Cytoskeleton·C M WhiteheadJ B Rattner
Aug 26, 1998·Biochimica Et Biophysica Acta·N Cabrera-PochD T Shima
Dec 30, 1999·The Journal of Cell Biology·S J VidwansP H O'Farrell
May 10, 2000·Trends in Cell Biology·D N Robinson, J A Spudich
Aug 19, 2000·Molecular Cell·G PereiraE Schiebel
Sep 7, 2000·Cell·M A Hoyt
Feb 13, 2001·Trends in Cell Biology·D McCollum, K L Gould
Feb 27, 2001·Science·M PielM Bornens
Jul 14, 2001·Molecular Biology of the Cell·K Chabin-BrionC Poüs
Feb 1, 1960·The Journal of Biophysical and Biochemical Cytology·D MaziaT Bibring

❮ Previous
Next ❯

Citations

Aug 17, 2004·DNA and Cell Biology·Qiang WangMark I Greene
May 25, 2010·BMC Cell Biology·Asta Björk JonsdottirKaroly Szuhai
Apr 18, 2006·Proceedings of the National Academy of Sciences of the United States of America·Qiang WangMark I Greene
Dec 3, 2003·Cell Motility and the Cytoskeleton·Young OuJerome B Rattner
Apr 4, 2006·Developmental Biology·Frantisek BaluskaPeter W Barlow
Sep 25, 2004·Radiation Research·Lynda FletcherRuth J Muschel
Sep 6, 2002·Oncogene·David V HansenAdam G Eldridge

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.