Post-mortem microbiology in sudden death: sampling protocols proposed in different clinical settings

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
A Fernández-RodríguezESGFOR and the ESP

Abstract

Autopsies, including minimally invasive autopsies, are a powerful tool for determination of the cause of death. When a patient dies from an infection, microbiology is crucial to identify the causative organism. Post-mortem microbiology (PMM) aims to detect unexpected infections causing sudden deaths; confirm clinically suspected but unproven infection; evaluate the efficacy of antimicrobial therapy; identify emergent pathogens; and recognize medical errors. Additionally, the analysis of the thanatomicrobiome may help to estimate the post-mortem interval. The aim was to provide advice in the collection of PMM samples and to propose sampling guidelines for microbiologists advising autopsy pathologists facing different sudden death scenarios. A multidisciplinary team with experts in various fields of microbiology and autopsies on behalf of the ESGFOR (ESCMID - European Society of Clinical Microbiology and Infectious Diseases - study group of forensic and post-mortem microbiology and in collaboration with the European Society of Pathology) developed this narrative review based on a literature search using MedLine and Scopus electronic databases supplemented with their own expertise. These guidelines address measures to prevent samp...Continue Reading

Citations

Jun 25, 2020·Forensic Science, Medicine, and Pathology·Caitlin Gilsenan-ReedNeil Langlois
Sep 6, 2020·Applied and Environmental Microbiology·Manuel G GarcíaIsabel Legaz
Nov 21, 2020·Medicine, Science, and the Law·Emily Bosco, Neil Langlois
Nov 30, 2018·Analytical Chemistry·Bruce R McCordGeorge Duncan
Dec 16, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Jana M RitterRoosecelis B Martines

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