PMID: 30173231Sep 3, 2018Paper

Post mortem troponin T analysis in sudden death: Is it useful?

The Malaysian Journal of Pathology
Razuin RahimiS Md Noor

Abstract

Cardiac-related diseases contributed approximately 50-60% of sudden natural death cases. This study aimed to describe the cardiac troponin T (cTnT) findings in post mortem subjects irrespective of the cause and manner of death, and the possible use of post mortem serum cTnT as a modality in investigating sudden natural death. The study samples comprised 140 subjects aged 18 to 50 years old, natural and unnatural causes of sudden death brought to the Department of Forensic Medicine, Hospital Sungai Buloh (HSgB) and Hospital Sultanah Aminah Johor Bahru (HSAJB) for a period of 12 months. The subjects were categorised into 5 groups: cardiovascular disease (CVD), sudden unexplained death (SUD), thoracic trauma (TT), non-thoracic trauma (NTT) and other diseases (OD). Median troponin concentration in cases of CVD, SUD, TT, NTT, and OD were 0.51 μg/L, 0.17 μg/L, 0.62 μg/L, 0.90 μg/L and 0.51 μg/L respectively. We found no significant difference of troponin T level in different causes of death (p ≥ 0.05). NTT has the highest median troponin concentration with 0.90 μg/L, SUD possessed the lowest median concentration with 0.17 μg/L. Troponin T is neither specific nor useful as cardiac biomarker for post mortem sample. Therefore, it may no...Continue Reading

Related Concepts

Related Feeds

Biomarkers for Cardiovascular Risk Assessment

Sensitive and accurate biomarkers used in cardiovascular risk prediction can potentially be used to manage the risk of cardiovascular disease. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here.

Related Papers

Forensic Science International : Synergy
S RemmerM Väli
Journal of Atherosclerosis and Thrombosis
Razuin RahimiHapizah Mohd Nawawi
The Malaysian Journal of Medical Sciences : MJMS
Sharon Casilda Theophilus, Johari Siregar Adnan
The American Journal of Forensic Medicine and Pathology
Christian Lycke Ellingsen, Øyvind Hetland
© 2022 Meta ULC. All rights reserved