Abstract
We analyzed the effect of nitroglycerin on radial artery occlusion (RAO) in women undergoing transradial catheterization. A total of 1706 patients undergoing transradial catheterization were randomized to receive either 500μg intra-arterial nitroglycerin or placebo at the end of the radial procedure. We explored the gender-based analysis between women (n=539) and men (n=1167). The primary outcome was the incidence of RAO as confirmed by absence of antegrade flow at one day after the transradial procedure evaluated by duplex ultrasound of the radial artery. The use of nitroglycerin, as compared with placebo, did not significantly reduce the risk of RAO in women patients [odds ratio, 0.69; 95% confidence interval (CI), 0.38 to 1.26; P=0.147]. The risk of RAO was higher in women age <60years as compared with women age ≥60years [5.6% vs. 3.5%; odds ratio, 2.16; 95% CI, 1.18 to 3.94; P=0.008]. In women age <60years (n=237), both counter puncture technique and a duration of hemostasis ≥4h were associated with a similar enhanced risk of developing RAO (odds ratio, 3.51; 95% CI, 1.59 to 7.72; P<0.001). The administration of nitroglycerin at the end of a transradial catheterization in women did not reduce the risk of RAO as determined b...Continue Reading
References
May 29, 1999·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·S SaitoS Tanaka
Dec 6, 2006·Circulation·Olivier F BertrandUNKNOWN Early Discharge After Transradial Stenting of Coronary Arteries Study Investigators
Jun 27, 2008·Pharmacological Reviews·Virginia M Miller, Sue P Duckles
Aug 30, 2008·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Samir PancholyMarie Roke-Thomas
Feb 21, 2009·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Jose M CuberoLuis F Pastor
May 28, 2010·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Sylvain PlanteOlivier F Bertrand
Jul 28, 2010·Journal of cardiovascular ultrasound·Kyu Seop KimJae-Hyeong Park
Oct 13, 2010·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Avtandil Babunashvili, David Dundua
Mar 29, 2011·The American Journal of Cardiology·Ivo BernatOlivier Costerousse
May 18, 2011·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Samir B Pancholy, Tejas M Patel
Mar 16, 2012·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Samir B PancholyTejas M Patel
Jun 12, 2013·Circulation·Dmitriy N FeldmanSunil V Rao
Sep 3, 2014·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Surya DharmaIan C Gilchrist