[Post-resuscitation syndrome. Role of inflammation after cardiac arrest].

Der Anaesthesist
A SchneiderP Teschendorf

Abstract

Cardiac arrest with subsequent cardiopulmonary resuscitation causes an ischemic reperfusion syndrome of the whole body resulting in localized damage of particularly sensitive organs, such as the brain and heart, together with systemic sequelae. The main factor is a generalized activation of inflammatory reactions resulting in symptoms similar in many aspects to those of sepsis. Systemic inflammation strengthens organ damage due to disorders in the macrocirculation and microcirculation due to metabolic imbalance as well as the effects of direct leukocyte transmitted tissue destruction. The current article gives an overview on the role of inflammation following cardiac arrest and presents in detail the underlying mechanisms, the clinical symptoms and possible therapeutic approaches.

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Citations

Dec 17, 2015·Herzschrittmachertherapie & Elektrophysiologie·Martin ChristHans-Joachim Trappe
Apr 22, 2015·Der Anaesthesist·M P MüllerJ Wnent
Apr 14, 2018·Critical Care Medicine·Alessandro BellettiGiovanni Landoni
Jun 6, 2018·BMC Anesthesiology·Daniel C SchroederMaria Guschlbauer
Apr 7, 2019·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Licai LiangPeng Sun
Sep 3, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Guanghui ZhengWanchun Tang

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