Post SARS-CoV-2 infection reactive arthritis: a brief report of two pediatric cases.

Pediatric Rheumatology Online Journal
Reza SinaeiNava Gharaei

Abstract

Although, preliminary reports of Severe Acute Respiratory Syndrome (SARS)-CoV-2 infection suggest that the infection causes a less severe illness in children, there is now growing evidence of other rare or even serious complications of disease. During the recent COVID-19 pandemic in Kerman, Iran, two children (an 8 year-old boy and a 6 year-old girl) were referred to outpatient Clinic of Pediatric Rheumatology with complaints of limping. Both children had experienced fever and mild respiratory tract infection. At the beginning of the second week of infection, they developed joint effusion. They both tested positive for coronavirus infection and were therefore diagnosed with post Coronavirus reactive arthritis. Both children were treated successfully with rest and Non-Steroidal Anti-Inflammatory Drugs (NSAID). They did not have any medical problems in the two months fallow up. These two cases suggest that COVID-19 may be rheumatogenic. Highlighting the need for awareness of physicians, especially pediatricians, regarding the pathogenesis margins of this virus, as late presentations are of great importance.

References

Apr 30, 2003·Arthritis Research & Therapy·Charles J CoxJ S Hill Gaston
Feb 12, 2010·Pediatric Rheumatology Online Journal·Normi BruckFrank Pessler
Dec 19, 2015·Pediatric Annals·Ami P ShahDeepak Kamat
Apr 3, 2016·Clinical Medicine : Journal of the Royal College of Physicians of London·Michael Marks, Jonathan L Marks
May 10, 2020·BMC Infectious Diseases·Li-Juan MaoZhe-Feng Yuan
Jul 1, 2020·The New England Journal of Medicine·Leora R FeldsteinUNKNOWN CDC COVID-19 Response Team
Sep 27, 2020·World Journal of Pediatrics : WJP·Reza SinaeiRoya Sinaei

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