Post-transcriptional regulation of gene expression in the plasminogen activation system

Biological Chemistry
Nunzia MontuoriPia Ragno

Abstract

The urokinase-mediated plasminogen activation (PA) system has been shown to play a key role in cell migration and tissue invasion by regulating both cell-associated proteolysis and cell-cell and cell-matrix interactions. The expression and activity of the components of this complex system are strictly regulated. The control of the expression occurs both at transcriptional and post-transcriptional levels. This review is focused on the post-transcriptional regulation of gene expression of all components of the PA system.

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Citations

Mar 16, 2005·Biochemical and Biophysical Research Communications·Thomas A Hughes, Hugh J M Brady
Nov 3, 2010·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Nathaniel JilletteRaymond P Henry
Dec 15, 2012·Thrombosis and Haemostasis·Nunzia MontuoriPia Ragno
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Jun 18, 2015·Journal of Cellular and Molecular Medicine·Daniela AlfanoPia Ragno

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