Post-traumatic stress disorder and amygdala-hippocampectomy

Acta Psychiatrica Scandinavica
P AdamiA Conca

Abstract

The case report suggests the indispensability of preoperative accurate psychiatric checkups especially in temporal resections. A single case was reported. We report the case of a 20-year-old woman suffering for 12 years from primary generalized epilepsy, attributed to left-sided hippocampal sclerosis. Because seizures were resistant to drug therapy, she underwent amygdala-hippocampectomy at the age of 18. Furthermore, she had previously been victim of childhood sexual abuse. Two weeks after epilepsy surgery, she manifested symptoms of post-traumatic stress disorder (PTSD). There is evidence that the amygdala-hippocampal region is both functionally and morphologically involved in the aetiology of PTSD. The removal of this marked neuroanatomical region and the resulting disconnection and asymmetry between right and left amygdala-hippocampal region might be seen as an evidence for this region aetiologically being involved in the patient's PTSD symptoms.

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Citations

May 21, 2008·Journal of Abnormal Psychology·Stephen D SmithDavid H Zald
Apr 11, 2009·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Michael Koenigs, Jordan Grafman
Jun 15, 2010·Epilepsy & Behavior : E&B·Sophia A HalleySarah J Wilson
Nov 14, 2007·Acta Psychiatrica Scandinavica·W V R ViewegA K Pandurangi
May 25, 2010·Journal of the American Academy of Child and Adolescent Psychiatry·Wouter GroenIndira Tendolkar
May 12, 2017·Frontiers in Behavioral Neuroscience·Fang HanYuxiu Shi

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