Postarthroscopic meniscus repair analgesia with intraarticular ketorolac or morphine

Anesthesia and Analgesia
S S Reuben, N R Connelly

Abstract

Both ketorolac, a nonsteroidal antiinflammatory drug, and morphine, an opioid agonist, provide enhanced patient analgesia after arthroscopic knee surgery when administered via the intraarticular route. This study was designed to determine whether ketorolac or morphine results in better patient analgesia and whether their combination would provide superior analgesia to either drug alone. Patients undergoing arthroscopic knee meniscus repair under local anesthesia with sedation were evaluated. Each of the study groups evaluated received ketorolac (either via the parenteral or intraarticular route) and morphine (via either the parenteral or intraarticular route). This study revealed a significant benefit from the individual intraarticular administration of both morphine and ketorolac. The combination of these drugs did not result in decreased postoperative pain or need for postoperative analgesics, and it did not result in an increased analgesic duration. We conclude that the use of either intraarticular ketorolac or intraarticular morphine improves the comfort in patients undergoing arthroscopic meniscus repair and that their combination offers no advantage over either drug alone.

Citations

Aug 12, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·S T ColbertM McCarroll
Apr 3, 2002·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Mordechai KligmanMoshe Roffman
Jun 16, 2004·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·J CalmetJ Giné
Jan 13, 2005·Archives of Orthopaedic and Trauma Surgery·Hanife AltunkayaAhmet Bayar
Jan 8, 2000·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·N M GrahamI Talkhani
Jul 17, 1998·Anesthesiology·N R Connelly, S S Reuben
Apr 9, 1999·Anesthesia and Analgesia·S S Reuben, N R Connelly
Feb 13, 2001·Anesthesia and Analgesia·S S Reuben
Feb 26, 2011·Anesthesia and Analgesia·Paul F WhiteUNKNOWN Editorial Board of Anesthesia & Analgesia
Mar 7, 2007·CNS Drugs·Srinivas Pyati, Tong J Gan
Apr 6, 2011·Journal of the Medical Library Association : JMLA·Kath Wright, Catriona McDaid
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