PMID: 2106340Jan 1, 1990Paper

Postenucleation orbital radiotherapy for the treatment of malignant melanoma of the choroid with extrascleral extension

The British Journal of Ophthalmology
P G HykinJ L Hungerford

Abstract

The outcome is reported in 17 patients in whom an eye was enucleated for malignant melanoma of the choroid with extrascleral extension and who subsequently underwent adjuvant external beam radiotherapy to the orbit as the primary treatment of the extraocular spread of their tumour. Extrascleral extension was encapsulated in five, non-encapsulated in two, and had been surgically transected at enucleation in 10 cases. All the patients have been followed up from enucleation to the present day. Orbital recurrence occurred in only one patient. The overall actuarial survival rate was 51% at 5 years, 44% at 10, and 33% at 15 years. A low orbital recurrence rate of 6% compares very favourably with published figures for this event after enucleation for melanoma with extrascleral extension but without radiotherapy. Adjuvant orbital radiotherapy may have a place in the treatment of selected cases of extracleral extension of intraocular malignant melanoma.

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Citations

Jul 2, 2003·American Journal of Ophthalmology·Dennis M Robertson
Dec 24, 1997·Survey of Ophthalmology·P T Finger
Oct 24, 2006·The British Journal of Ophthalmology·K L LinP T Finger
May 1, 1992·The British Journal of Ophthalmology·P N Plowman
Jun 1, 1992·The British Journal of Ophthalmology·A D ParidaensJ L Hungerford
Jul 1, 1994·The British Journal of Ophthalmology·A D ParidaensJ L Hungerford
Aug 26, 2004·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·James J AugsburgerNikolaos Trichopoulos
Aug 26, 2004·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Gonzalo Blanco
Jan 28, 2009·Survey of Ophthalmology·Nathan M Radcliffe, Paul T Finger
Nov 1, 1991·Survey of Ophthalmology·J A ShieldsL A Donoso
Sep 1, 2001·American Journal of Ophthalmology·P T Finger
Aug 31, 2000·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·S LiarikosA P Angelopoulos
Sep 21, 2004·Ophthalmic Plastic and Reconstructive Surgery·Hossein SaadatiBita Esmaeli
Jan 10, 2018·Orbit·Christopher K H BurrisVictoria M L Cohen
Jul 23, 2008·Ophthalmic Plastic and Reconstructive Surgery·Marsha C KavanaghJill A Foster
Dec 21, 2018·BMJ Case Reports·Pallavi SinghRachna Meel
Oct 4, 2020·Ophthalmic Plastic and Reconstructive Surgery·Kelsey A RoelofsBertil Damato

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