Postepizootic Persistence of Asymptomatic Mycoplasma conjunctivae Infection in Iberian Ibex

Applied and Environmental Microbiology
Xavier Fernández-AguilarJorge R López-Olvera

Abstract

The susceptibility of the Iberian ibex (Capra pyrenaica) to Mycoplasma conjunctivae ocular infection and the changes in their interaction over time were studied in terms of clinical outcome, molecular detection, and IgG immune response in a captive population that underwent a severe infectious keratoconjunctivitis (IKC) outbreak. Mycoplasma conjunctivae was detected in the Iberian ibex, coinciding with the IKC outbreak. Its prevalence had a decreasing trend in 2013 that was consistent with the clinical resolution (August, 35.4%; September, 8.7%; November, 4.3%). Infections without clinical outcome were, however, still detected in the last handling in November. Sequencing and cluster analyses of the M. conjunctivae strains found 1 year later in the ibex population confirmed the persistence of the same strain lineage that caused the IKC outbreak but with a high prevalence (75.3%) of mostly asymptomatic infections and with lower DNA load of M. conjunctivae in the eyes (mean quantitative PCR [qPCR] cycle threshold [CT ], 36.1 versus 20.3 in severe IKC). Significant age-related differences of M. conjunctivae prevalence were observed only under IKC epizootic conditions. No substantial effect of systemic IgG on M. conjunctivae DNA in ...Continue Reading

References

Aug 21, 1976·The Veterinary Record·G E JonesD B Harker
Mar 7, 1987·The Veterinary Record·A H AndrewsG J Dagnell
Oct 1, 1973·The Australian Journal of Experimental Biology and Medical Science·P G Surman
Jan 1, 1984·Journal of Molecular Evolution·C R WoeseW Ludwig
Aug 1, 1993·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J W SimeckaJ K Davis
Jul 1, 1997·Journal of Wildlife Diseases·D MayerM Giacometti
Dec 10, 1998·Trends in Microbiology·S Rottem, Y Naot
Nov 26, 1999·Journal of Wildlife Diseases·L León-VizcaínoF Alonso
Oct 24, 2000·International Journal of Medical Microbiology : IJMM·R RosengartenJ Spergser
Aug 29, 2001·Veterinary Microbiology·M JanovskyM Giacometti
Apr 27, 2002·Revue Scientifique Et Technique·M GiacomettiJ Frey
Jun 1, 2002·Journal of Wildlife Diseases·Marco GiacomettiJoachim Frey
Apr 5, 2003·Applied and Environmental Microbiology·Luc BelloyJoachim Frey
May 17, 2006·Trends in Ecology & Evolution·Jerald B Johnson, Kristian S Omland
Jul 28, 2006·Journal of Wildlife Diseases·Mónica González-CandelaLuis León-Vizcaíno
Jan 9, 2008·Journal of Evolutionary Biology·S A Frank, P Schmid-Hempel
Aug 20, 2008·The American Naturalist·Samuel Alizon
Dec 17, 2008·Future Microbiology·Ken B WaitesT Prescott Atkinson
Jul 17, 2010·Future Microbiology·Christine CittiEric Baranowski
Feb 20, 2013·Trends in Microbiology·Christine Citti, Alain Blanchard
Dec 18, 2013·BMC Veterinary Research·Xavier Fernández-AguilarJorge R López-Olvera
Apr 23, 2014·Journal of Evolutionary Biology·P D WilliamsA A Dhondt
Feb 13, 2015·The American Naturalist·Erik E OsnasAndrew P Dobson
Mar 24, 2016·Molecular Biology and Evolution·Sudhir KumarKoichiro Tamura
Apr 27, 2016·Proceedings of the National Academy of Sciences of the United States of America·Yonathan ArfiPascal Sirand-Pugnet
Sep 1, 1987·Revue Scientifique Et Technique·M C Lambert

❮ Previous
Next ❯

Citations

Oct 11, 2017·PloS One·Xavier Fernández-AguilarJorge Ramón López-Olvera
Jun 24, 2020·Transboundary and Emerging Diseases·Félix Gómez-GuillamónIgnacio García-Bocanegra
Dec 14, 2018·International Journal of Systematic and Evolutionary Microbiology·Dmitriy V VolokhovVladimir E Chizhikov

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.