Poster - Thurs Eve-14: Linking IGRT data with dose calculation for prostate IMRT planning

Medical Physics
R JiangE K Osei

Abstract

Internal organ motion was studied for 20 prostate patients who were treated with IGRT using MV EPI with three gold seeds implanted in the prostate. Prostate motion was determined from the gold seed displacement relative to bony anatomy between the EPI and the DRR fraction-to-fraction before any correction was applied. The patients were planned with a tight 2mm PTV margin for seven-beam IMRT with prescribed dose of 82 Gy. Treatment planning incorporating organ motion was done manually by convolving the static dose distribution with patient-specific PDF. A Gaussian PDF is reasonable for modeling geometric uncertainties. In the anterior and superior directions, dose decreased more than 5% on the edge of PTV for 5% of the patients. While in inferior direction the dose decreased more than 5% on the edge of PTV for 15% of the patients. The PTV dose is lower than 95% prescription dose for 10% of the patient incorporating individual IGRT data. While for applying group PDF, the dose satisfied the minimum 95% of PTV dose, so group PDF should not be used for accurate treatment planning evaluation for individual patients. Static dose distribution is insufficient to assess PTV coverage. The inclusion of organ motion on dose distribution is ...Continue Reading

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