Posterior fossa lateral ependymoma in childhood

Pediatric Neurosurgery
M G Nagib, M T O'Fallon

Abstract

Over a period extending from 1984 to 1993, 16 children ranging in ages from 2 months to 12 years with posterior fossa ependymoma were treated. Four of these tumors were classified as lateral ependymomas because of their configuration and suspected site of origin. These 4 patients' ages ranged from 2 months to 5 years. Signs and symptoms of increased intracranial pressure and cranial nerve dysfunction were the hallmark of their presentation. Their imaging evaluation included a preoperative and postoperative CT san and/or MRI. A gross total surgical resection' was completed in the 4 children. At least a 1-year follow-up was available for all the patients. Intraoperative brain stem evoked potentials and facial and glossopharyngeal nerve monitoring were used in all the surgeries. Three children required a ventriculoperitoneal shunt postoperatively. Chemotherapy was used postoperatively in 3 children. The 4th child did not receive chemotherapy due to parental refusal and succumbed to a recurrence 1 years postoperatively. Radiation therapy was given to 2 children. Tumor recurrences developed in all children at 12 months, 18 months, 3 years and 4 years postoperatively in proximity to the original tumor site. Histologic sections in 3 p...Continue Reading

Citations

May 22, 2008·Der Radiologe·M SinzigK A Hausegger
Apr 11, 2009·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Kazuaki ShimojiHajime Arai
Apr 11, 2009·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·E L YuhN Gupta
Dec 31, 2002·Pediatric Neurology·Hart Isaacs
Aug 5, 2003·Paediatric Drugs·Jacques GrillKalifa Chantal
Apr 2, 2013·Journal of Neurosurgery. Pediatrics·Tene A CageKurtis I Auguste
May 27, 2006·Neurosurgical Focus·R G Ellenbogen
Oct 3, 2000·Journal of Neurosurgery·D Figarella-BrangerJ F Pellissier
Oct 3, 2000·Journal of Neurosurgery·R J Packer
Dec 2, 2014·Pediatric Clinics of North America·Murali Chintagumpala, Amar Gajjar
Apr 28, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Noah D SabinRobert J Ogg
Oct 23, 2021·AJNR. American Journal of Neuroradiology·N D SabinD W Ellison

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