Posterior pelvic exenteration for primary rectal cancer

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
G C BannuraJ E Mansilla

Abstract

Indications for and the prognosis of posterior pelvic exenteration (PPE) in rectal cancer patients are not clearly defined. The aim of this study was to analyse the indications, complications and long-term results of PPE in patients with primary rectal cancer. A retrospective review included patient demographics, tumour and treatment variables, and morbidity, recurrence, and survival statistics. These results were compared with a group of female patients who underwent standard resection for primary rectal cancer in the same period (non PPE group). The series included 30 women with an average age of 56.7 years (range 22-78). Tumour location was recorded in three cases in the upper rectum, 13 cases in the medium rectum and 14 cases in the lower rectum. A sphincter-preserving procedure was performed in 70% of the patients. Mean operative time was 4.2 h (range 2-7.5 h). Overall major morbidity rate in this series was 50% and mean hospital stay was 19.7 days (range 9-60 days). There was no hospital mortality. Pathological reports showed direct invasion of uterus, vagina or rectovaginal septum in 19 cases, involvement of perirectal tissue in 25 cases and positive lymph nodes in 18 cases. Comparison between PPE and non PPE groups show...Continue Reading

References

Sep 1, 1979·American Journal of Surgery·F E EckhauserG W Morley
Jan 1, 1992·Annals of Surgery·G H HafnerN J Petrelli
Nov 1, 1985·Archives of Surgery·J G JakowatzJ D Beatty
Apr 1, 1982·Annals of Surgery·J BoeyG B Ong
Apr 1, 1994·American Journal of Surgery·P F BrophyB L Eisenberg
Feb 1, 1996·American Journal of Surgery·M A Rodriguwz-Bigas, N J Petrelli
Oct 3, 1999·Seminars in Surgical Oncology·J G PetrosM J Lopez
Oct 16, 2004·Diseases of the Colon and Rectum·Graham BranaganDerek Finnis

❮ Previous
Next ❯

Citations

Sep 3, 2013·Indian Journal of Surgical Oncology·Rajaraman Ramamurthy, Amudhan Duraipandian
May 15, 2013·Annals of Surgical Oncology·H M MohanD C Winter
Feb 9, 2012·International Journal of Surgical Oncology·Mansel Leigh DaviesJohn Beynon
Oct 23, 2010·Journal of Minimally Invasive Gynecology·Shailesh PuntambekarAvanish Deshmukh
Mar 13, 2013·Diseases of the Colon and Rectum·Timothy X YangTerence C Chua
Dec 13, 2018·Indian Journal of Surgical Oncology·Iosifina KarmaniolouVassilios Smyrniotis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.