Posterior Tibial Nerve Stimulation for the Treatment of Fecal Incontinence Following Obstetric Anal Sphincter Injury

Neuromodulation : Journal of the International Neuromodulation Society
Santosh SanagapalliA V Emmanuel

Abstract

Obstetric anal sphincter injuries (OASI) are a major risk factor for fecal incontinence (FI). Neuromodulation is often used as second-line therapy for FI, but evidence for its efficacy is conflicting. We aimed to evaluate the efficacy and predictive factors of posterior tibial nerve stimulation for obstetric anal sphincter injury-induced FI. Consecutive females with FI related to past OASI who had not responded to first-line therapy and had received 8-12 weeks of posterior tibial nerve stimulation were included. Subjects aged more than 50 and/or having other causes of FI were excluded. Patients underwent anorectal physiology and endoanal ultrasound pretherapy. Symptom burden was evaluated pretherapy and posttherapy using Rockwood and Wexner scales. A Wexner score reduced to below 10 or halved was used to define responders. A total of 37 females (mean age 38 years, median parity 2) were included. About 17 (46%) had ultrasonographically visualized anal sphincter defects and 41% had a history of third or second-degree perineal tears. About 14 subjects (38%) were deemed responders. Compared with nonresponders, responders had lower baseline rectal distension thresholds and tended to have disrupted (59%) than intact sphincters (20%, ...Continue Reading

References

Jan 24, 2002·Diseases of the Colon and Rectum·J RothbarthJ B Delemarre
Apr 8, 2003·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·A ShafikR M Mostafa
Nov 5, 2003·Gastroenterology·Christine NortonMichael A Kamm
Aug 17, 2004·The American Journal of Gastroenterology·Satish S C Rao, UNKNOWN American College of Gastroenterology Practice Parameters Committee
Feb 5, 2005·Diseases of the Colon and Rectum·Christopher L H ChanPeter J Lunniss
Jan 22, 2008·Diseases of the Colon and Rectum·Takeshi Takahashi-MonroyLiliana Velasco
Jan 25, 2008·Annals of Surgery·Thomas C DuddingMichael A Kamm
Aug 14, 2009·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·B GovaertC G Baeten
Nov 9, 2010·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Fiona MarshWright Alison
Feb 1, 2011·International Journal of Colorectal Disease·Emile TanParis P Tekkis
Jun 22, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·G GourcerolM Bouvier
Aug 10, 2011·Diseases of the Colon and Rectum·Giuseppe PreziosiAnton Emmanuel
Mar 2, 2012·Clinics in Colon and Rectal Surgery·Dana M Hayden, Eric G Weiss
Dec 12, 2012·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·G P ThomasC J Vaizey
Jan 22, 2014·The British Journal of Surgery·E J HorrocksC H Knowles
Jan 24, 2014·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C J Vaizey
Feb 19, 2014·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Arnold Wald
May 20, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·A MellgrenUNKNOWN Nasha Dx Study Group
Sep 17, 2014·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·J FassovK Krogh
Jan 16, 2015·Clinical and Translational Gastroenterology·Jaime E SanchezCraig Paterson
Jan 16, 2016·Therapeutic Advances in Gastroenterology·Jakob Duelund-JakobsenKlaus Krogh
Jul 28, 2016·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M B RydningenS Norderval

❮ Previous
Next ❯

Citations

Dec 29, 2020·Behavioural Brain Research·Dayana HayekAgnes Flöel
Jun 11, 2021·Journal of Gynecology Obstetrics and Human Reproduction·Bertrand GachonXavier Fritel

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anorexia Nervosa

Anorexia nervosa (AN) is a psychiatric condition characterized by severe weight loss and secondary problems associated with malnutrition. Here is the latest research on AN.