PMID: 7041623Apr 1, 1982Paper

Postextubation nasal continuous positive airway pressure. A prospective controlled study

American Journal of Diseases of Children
S C EngelkeL R Kuhns

Abstract

Nasal continuous positive airway pressure (N-CPAP), applied immediately after extubation, was prospectively evaluated in 18 neonates recovering from respiratory distress syndrome. Patients were randomly assigned to N-CPAP (group 1, N=9) or a control group given oxygen by hood (group 2, N=9). Groups were comparable in birth weight and duration of intubation. In the 24-hour period following extubation, group 1 showed a significantly lower mean respiratory rate (46 +/- 2 vs 74 +/- 4), alveolar-arterial oxygen gradient (94 +/- 9 vs 134 +/- 12 mm Hg), PCO2 (45 +/- 1 vs 50 +/- 1 mm Hg), higher pH (7.33 +/- 0.01 vs 7.30 +/- 0.01), and less atelectasis by roentgenographic scores. This was associated with considerably better clinical courses in group 1 when compared with group 2, in which six patients required a late trial of N-CPAP because of respiratory deterioration and two patients needed reintubation. Postextubation N-CPAP has a striking beneficial effect on respiratory function and prevention of atelectasis.

Citations

May 1, 1993·Archives of Disease in Childhood·V Chan, A Greenough
May 1, 1995·Archives of Disease in Childhood. Fetal and Neonatal Edition·B H SoS Kamoshita
Nov 3, 1998·Archives of Disease in Childhood. Fetal and Neonatal Edition·P DavisP Henschke
Aug 17, 1999·Archives of Disease in Childhood. Fetal and Neonatal Edition·C Morley
Jun 29, 2000·Archives of Disease in Childhood. Fetal and Neonatal Edition·S K Sinha, S M Donn
Jun 1, 1992·Acta Paediatrica Japonica; Overseas Edition·B H SoS Kamoshita
Apr 1, 1996·Pediatric Pulmonology·S Al-AlaiyanB Khan
Dec 17, 2011·European Journal of Pediatrics·Olie ChowdhuryAnne Greenough
Sep 21, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Zelal KahramanerEsra Arun Ozer
Aug 1, 1999·Journal of Paediatrics and Child Health·P G Davis, D J Henderson-Smart
Apr 1, 1993·The Annals of Otology, Rhinology & Laryngology. Supplement·B Benjamin
Jun 14, 2003·The Cochrane Database of Systematic Reviews·P G Davis, D J Henderson-Smart
Sep 1, 1993·Pediatric Pulmonology·W J SoongR B Tang
Jul 28, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Numan Nafie HameedOla Didrik Saugstad
Jul 18, 2018·The Annals of Otology, Rhinology, and Laryngology·Bruce Benjamin
Apr 21, 2006·Journal of Perinatology : Official Journal of the California Perinatal Association·E Bancalari, T del Moral
Nov 16, 2007·The Journal of Perinatal & Neonatal Nursing·Debbie Fraser Askin
Aug 2, 2015·European Journal of Pediatrics·Yue YinDavid A Todd
May 5, 2000·The Cochrane Database of Systematic Reviews·P G Davis, D J Henderson-Smart

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