Postgenomic taxonomy of human ureaplasmas -- a case study based on multiple gene sequences

International Journal of Systematic and Evolutionary Microbiology
Fanrong Kong, Gwendolyn L Gilbert

Abstract

In 2000, the full genome sequence of Ureaplasma parvum (previously known as Ureaplasma urealyticum) serovar 3 was released. In 2002, after prolonged debate, it was agreed that the former U. urealyticum should be divided into two species -- U. parvum and U. urealyticum. To provide additional support for this decision and improve our understanding of the relationship between these two species, the authors studied four 'core' genes or gene clusters in ATCC reference strains of all 14 serovars of U. parvum and U. urealyticum. These 'core' regions were the rRNA gene clusters, the EF-Tu genes (tuf), urease gene clusters and multiple-banded antigen genes (mba). The known U. parvum genome sequences (GenBank accession no. NC_002162) were used as reference. DNA insertions and deletions (indels) were found in all of the gene regions studied, except tuf, but they were found only between, not within, the two species. An incidental finding was that there was inter-copy heterogeneity for rRNA gene cluster sequences. Sequence analysis (sequence heterogeneity and especially indels) of all four selected targets consistently supported the separation of human ureaplasmas into two species. Except for multiple-banded antigen, there was less heteroge...Continue Reading

References

Mar 25, 1990·Nucleic Acids Research·J A RobertsonL R Finch
Jun 1, 1984·Journal of Clinical Microbiology·J A Robertson, M H Chen
Oct 20, 1995·Science·C M FraserJ C Venter
Jan 1, 1994·International Journal of Systematic Bacteriology·R G Murray, K H Schleifer
Nov 15, 1996·Nucleic Acids Research·R HimmelreichR Herrmann
May 20, 1998·Electrophoresis·W LudwigK H Schleifer
Sep 12, 1998·International Journal of Systematic Bacteriology·T MygindG Christiansen
Nov 26, 1998·International Journal of Systematic Bacteriology·C L KnoxP Timms
Dec 29, 1998·Journal of Bacteriology·K UedaM Kataoka
Jun 3, 1999·Journal of Microbiological Methods·J García-MartínezF Rodríguez-Valera
Nov 11, 1999·International Journal of Systematic Bacteriology·F kongG L Gilbert
May 29, 2000·International Journal of Systematic and Evolutionary Microbiology·B PetterssonK E Johansson
Sep 22, 2000·Emerging Infectious Diseases·C M FraserS Peterson
Oct 18, 2000·International Journal of Systematic and Evolutionary Microbiology·F KongG L Gilbert
Feb 24, 2001·International Journal of Systematic and Evolutionary Microbiology·R M Bush, K D Everett
Feb 24, 2001·International Journal of Systematic and Evolutionary Microbiology·V Gürtler, B C Mayall
Jan 1, 1996·Cladistics : the International Journal of the Willi Hennig Society·D AgostiR DeSalle
Apr 5, 2002·International Journal of Systematic and Evolutionary Microbiology·Christophe MougelXavier Nesme
Apr 5, 2002·International Journal of Systematic and Evolutionary Microbiology·Janet A RobertsonDenys K Ford
Apr 10, 2002·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·K PovlsenI Lind
Apr 25, 2002·Nucleic Acids Research·Eduardo P C Rocha, Alain Blanchard
Jun 11, 2002·International Journal of Systematic and Evolutionary Microbiology·Erko StackebrandtWilliam B Whitman
Jul 20, 2002·Molecular Phylogenetics and Evolution·Mark P SimmonsJohn V Freudenstein
Aug 9, 2002·Theoretical Population Biology·Radhey S Gupta, Emma Griffiths
Aug 9, 2002·Theoretical Population Biology·Jeffrey G Lawrence
Mar 1, 2003·Nature Reviews. Genetics·Lindell Bromham, David Penny
Apr 4, 2003·Proceedings of the National Academy of Sciences of the United States of America·Roy J BrittenR Andrew Cameron
Sep 19, 2003·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·F DaxboeckC Wenisch
Jan 27, 2004·International Journal of Systematic and Evolutionary Microbiology·Franco DellaglioJacques-Edouard Germond

❮ Previous
Next ❯

Citations

Aug 19, 2008·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Meng DongyaWang Lu
Oct 31, 2008·Journal of Clinical Microbiology·Yiping W HanCatalin S Buhimschi
Jul 31, 2010·Infectious Diseases in Obstetrics and Gynecology·Alexander KaraulovAlexandra Bayrakova
Mar 7, 2020·Critical Reviews in Microbiology·Kaitlin Elizabeth SprongSharlene Govender
Nov 6, 2007·International Journal of Systematic and Evolutionary Microbiology·Daniel R BrownJanet M Bradbury

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.