Posthyperventilatory steal response in chronic cerebral hemodynamic stress: a positron emission tomography study

Stroke; a Journal of Cerebral Circulation
T NariaiK Hirakawa

Abstract

The alteration of regional cerebral blood flow (CBF) during and after hyperventilation was measured using positron emission tomography (PET) to determine the circulatory response induced by daily respiratory changes in the cerebral area under chronic hemodynamic stress. Three normal volunteers and 12 patients with an obstruction of major cerebral arteries underwent PET measurements of the CBF after an injection of H2(15)O: (1) in the resting condition, (2) during hyperventilation (HV scan), (3) 1 to 3 minutes after hyperventilation (post-HV scan), (4) during the inhalation of 5% CO2, and (5) after an injection of acetazolamide. Eleven patients also underwent a 15O gas study to measure CBF, oxygen extraction fraction (OEF), and cerebral blood volume (CBV). (1) In 9 patients, the CBF value in the post-HV scan was lower than that in the HV scan in 1 or more regions in the area of the obstructed arteries, although the PaCO2 level during the post-HV scan was higher than that during the HV scan in all patients. All control regions in the patients and in the normal volunteers showed an elevated CBF in the post-HV scan compared with the HV scan. (2) The negative post-HV response (posthyperventilatory steal) was prominent in 4 patients ...Continue Reading

References

Oct 1, 1978·Annals of Neurology·R L GrubbJ O Eichling
Mar 1, 1991·Annals of Neurology·W J Powers
Oct 1, 1990·Neurology·D A CarpenterW J Powers
Sep 1, 1989·AJR. American Journal of Roentgenology·J RoggR E Latchaw
Apr 1, 1988·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·I KannoI Sayama
Oct 1, 1988·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·M SendaR H Ackerman
Oct 1, 1986·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·H IidaK Uemura
Apr 1, 1987·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·I KannoK Uemura
May 1, 1987·Journal of Neurosurgery·A D MendelowW Fitch
Jan 1, 1986·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·M KameyamaT Ido
Dec 1, 1983·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·A A LammertsmaT Jones
Dec 1, 1983·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·A A Lammertsma, T Jones
Apr 1, 1995·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·S KurodaK Mitsumori
May 1, 1994·The American Journal of Physiology·M G MuhonenC M Loftus
Oct 1, 1993·Journal of Neurosurgery·H YonasD W Johnson

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Citations

Jan 21, 2006·Journal of Neuroradiology. Journal De Neuroradiologie·M WintermarkH Yonas
Feb 11, 2003·Critical Care Medicine·Jeannette HofmeijerL Jaap Kappelle
Apr 2, 2009·Neurosurgical Focus·Jodi L Smith
Apr 2, 2009·Neurosurgical Focus·Marco LeeGary K Steinberg
May 1, 2004·Radiology·Ellen G HoeffnerSuresh K Mukherji
Jan 13, 2005·Cerebrovascular Diseases·Peter HornMichael Hennerici
Jul 12, 2002·Journal of Magnetic Resonance Imaging : JMRI·Deniz BilecenErich Seifritz
May 11, 2011·Pediatric Neurology·Stuart CurriePaul D Griffiths
Aug 13, 2002·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Masashi TakasawaMasayasu Matsumoto
Dec 15, 2015·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Jai-Hyuck HanSang-Hoon Cha
Jul 17, 2007·Progress in Cardiovascular Diseases·Antonio Franco Folino
May 14, 2008·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Masahiro Mishina
Feb 15, 2001·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·S K PiechnikJ D Pickard
Feb 1, 2018·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Shinpei SatoKuniaki Ogasawara

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