Postinfectious cerebellitis: clinical significance of Tc-99m HMPAO brain SPECT compared with MRI

Clinical Nuclear Medicine
E C San PedroG Deutsch

Abstract

We compared Tc-99m HMPAO brain SPECT and MRI with the clinical findings in a case of a 14-year-old boy with post-infectious cerebellitis. Tc-99m HMPAO brain SPECT scan showed marked reduction in perfusion to the left anterior lobe, left lateral hemisphere, and left posterior lobe of the cerebellum. The MRI showed a limited region of abnormal signal in the mid posterior left cerebellar hemisphere. Since the patient's overall neurological deficit was characterized by ataxia, nystagmus, head and body titubation, dysmetria, dysdiadochokinesia, loss of normal check, and rebound testing attributed to the involvement of the anterior, lateral, and posterior lobes of the left cerebellar hemisphere, the Tc-99m HMPAO brain SPECT finding correlated better with the extent of functional neurological deficits. Tc-99m HMPAO brain SPECT may better assess cerebellar signs and symptoms in cerebellitis since the blood flow abnormalities correlated with dysfunction of the cerebellum, whereas the MRI abnormalities did not encompass the scope of the neurological deficits.

References

Jan 1, 1991·Pediatric Neurosurgery·M B HorowitzW Hirsch
May 1, 1994·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·J M MountzJ M Harris
Jan 1, 1993·Journal of Neurology·T KlockgetherJ Dichgans

❮ Previous
Next ❯

Citations

Mar 9, 2004·Clinical Neurology and Neurosurgery·Jeong Wook ParkKwang Soo Lee
Jan 24, 2004·Pediatric Neurology·Antigone S PapavasiliouStamos Trakadas
Nov 27, 2008·Clinical Nuclear Medicine·Pi-Lien HungYing-Chao Chang
May 1, 2012·Journal of Movement Disorders·Kang Min ParkSung Eun Kim
Oct 27, 2005·The British Journal of Radiology·J L F de MendoncaA C L Ferreira
Jul 29, 2008·Neurologic Clinics·Farshid NoorbakhshChristopher Power
Jul 23, 2003·Neurological Research·Peiyuan F HsiehMing-Hong Chang
Jun 11, 2015·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Adnan I QureshiKezely Beavogui
Nov 4, 2000·Journal of Child Neurology·K L HungM L Tsai

❮ Previous
Next ❯

Related Concepts

Related Feeds

Ataxia telangiectasia (MDS)

Ataxia telangiectasia is a rare neurodegenerative diseases caused by defects in the ATM gene, which is involved in DNA damage recognition and repair pathways. Here is the latest research on this autosomal recessive disease.

Ataxias

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on different types of ataxias here.

Ataxias (MDS)

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Ataxia

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Related Papers

Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine
Michito AdachiTakaaki Hosoya
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Maria CiardiSalvatore Delia
© 2022 Meta ULC. All rights reserved