PMID: 15231167Jul 3, 2004Paper

Postmarketing surveillance on Benazepril

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
Jun LuYong-hua Hu

Abstract

To investigate the long-term effect, safety and tolerability of benazepril in general hypertensive patients. We conducted a three-year community-based postmarketing surveillance on benazepril among 1831 essential hypertensive patients (age range from 35 to 88 years) in Shanghai. 74.3% of patients persisted in medication taking and were with optimal compliance in a 3-year-follow-up program. Among those taking medication as prescribed after 3 years, 75.7% of them attained systolic blood pressure (SBP) target level of 140 mm Hg (1 mm Hg = 0.133 kPa), 87.4% attained diastolic blood pressure (DBP) target level of 90 mm Hg, and 71.5% attained total target level of 140/90 mm Hg. The reductions were approaching 15 mm Hg for SBP, 10 mm Hg for DBP, and 5 mm Hg for pulse pressure (PP) during the 3 year period. No serious adverse drug reactions (ADRs) were detected during the 3 years follow-up. Cough was the most common ADR. The cumulative incidence of benazepril related cough was 23.6% in women, significant higher than in men (18.8%). Benazepril was safe and tolerable when applied in hypertensive patients.

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Related Papers

Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology
Jean-Louis PouchelonGünther Strehlau
Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology
BENCH (BENazepril in Canine Heart disease) Study Group
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
Jun LuYong-hua Hu
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
W CaoT Wang
© 2022 Meta ULC. All rights reserved