Postmortem biochemistry: Current applications

Journal of Forensic and Legal Medicine
S L Belsey, Robert J Flanagan


The results of biochemical analyses in specimens obtained postmortem may aid death investigation when diabetic and alcoholic ketoacidosis is suspected, when death may have been the result of drowning, anaphylaxis, or involved a prolonged stress response such as hypothermia, and in the diagnosis of disease processes such as inflammation, early myocardial infarction, or sepsis. There is often cross-over with different disciplines, in particular with clinical and forensic toxicology, since some endogenous substances such as sodium chloride, potassium chloride, and insulin can be used as poisons. The interpretation of results is often complicated because of the likelihood of postmortem change in analyte concentration or activity, and proper interpretation must take into account all the available evidence. The unpredictability of postmortem changes means that use of biochemical measurements in time of death estimation has little value. The use of vitreous humour is beneficial for many analytes as the eye is in a physically protected environment, this medium may be less affected by autolysis or microbial metabolism than blood, and the assays can be performed with due precaution using standard clinical chemistry analysers. However, in...Continue Reading


Jan 31, 1978·Zeitschrift für Rechtsmedizin. Journal of legal medicine·R van den Oever
Jun 1, 1985·Forensic Science International : Synergy·H Gormsen, A Lund
May 1, 1982·Forensic Science International : Synergy·H Sippel, M Möttönen
Feb 1, 1994·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·O Lundquist, S Osterlin
Jun 1, 1993·The American Journal of Forensic Medicine and Pathology·J I Coe
Sep 30, 1996·Forensic Science International : Synergy·D W SadlerD J Pounder
Jan 1, 1996·International Journal of Legal Medicine·J Hirvonen, P Huttunen
Mar 11, 1998·Forensic Science International : Synergy·E MüllerR Koch
Jul 1, 1998·International Journal of Legal Medicine·Eduardo OsunaAurelio Luna
Aug 26, 1998·Forensic Science International : Synergy·Erik Edston, Marianne van Hage-Hamsten
Aug 25, 1999·International Journal of Legal Medicine·Eduardo OsunaAurelio Luna
Jan 22, 2000·Epilepsia·K OpeskinS F Berkovic
Mar 4, 2000·Forensic Science International : Synergy·J E AzparrenM Andreu
Mar 29, 2000·Forensic Science International : Synergy·Eduardo OsunaAurelio Luna
May 24, 2000·Journal of Clinical Pathology·R S Pumphrey, I S Roberts
Nov 1, 2000·Forensic Science International : Synergy·H IwaseT Takatori
Nov 14, 2000·Forensic Science International : Synergy·B L ZhuH Maeda
May 18, 2001·International Journal of Legal Medicine·M TsokosK Püschel
May 25, 2001·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Adam BerkowiczHans Denison
Oct 24, 2001·Forensic Science International : Synergy·F WehnerJ Subke
Nov 7, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M G BuckleyA F Walls
Dec 14, 2001·Forensic Science International : Synergy·L Uhlin-Hansen
Jan 17, 2002·Forensic Science International : Synergy·F WehnerJ Subke
Dec 31, 2002·Forensic Science International : Synergy·Erik Edston, Marianne van Hage-Hamsten
Aug 29, 2003·Journal of Clinical Pathology·M A ParsonsA R W Forrest
Nov 12, 2003·Forensic Science International : Synergy·Adam BerkowiczHans Denison
Mar 19, 2004·Journal of Forensic Sciences·Angelique GagajewskiFred S Apple
Mar 1, 2005·Forensic Science International : Synergy·Hajime Nishio, Koichi Suzuki
Mar 1, 2005·International Journal of Legal Medicine·Hajime NishioKoichi Suzuki
Jun 9, 2005·Forensic Science International : Synergy·Burkhard Madea
Sep 6, 2005·Forensic Science International : Synergy·Eduardo OsunaMaría Dolores Pérez-Cárceles
Dec 28, 2005·Forensic Science International : Synergy·Michel H A Piette, Els A De Letter
Jan 28, 2006·Forensic Science International : Synergy·Burkhard Madea, Alexander Rödig
Feb 21, 2006·Journal of Clinical Forensic Medicine·Roger W ByardMichael Tsokos
Mar 28, 2006·Forensic Science International : Synergy·Gudrun HøisethJørg Mørland
May 20, 2006·International Journal of Legal Medicine·Erik EdstonMarianne van Hage
Jun 2, 2006·The American Journal of Forensic Medicine and Pathology·A Ben KhalifaT Mghirbi
Jun 20, 2006·Forensic Science International : Synergy·Burkhard Madea, F Musshoff
Jun 22, 2006·Forensic Science International : Synergy·Michael Tsokos
Aug 26, 2006·Immunology and Allergy Clinics of North America·Lawrence B Schwartz
Jan 16, 2007·Forensic Science International : Synergy·B S Astrup, J L Thomsen
May 4, 2007·Forensic Science International : Synergy·Juha RainioFranco Tagliaro
May 31, 2008·Journal of Forensic and Legal Medicine·Koichi UemuraKen-ichi Yoshida
Jun 17, 2008·Forensic Science International : Synergy·Takaki IshikawaHitoshi Maeda
Oct 14, 2008·Legal Medicine·Grzegorz TeresińskiRoman Madro
Sep 5, 2009·Forensic Science International : Synergy·Annette ThieraufBurkhard Madea
Mar 1, 2008·The American Journal of Forensic Medicine and Pathology·Ender SenolNeslihan Bukan
Nov 21, 2009·Forensic Science International : Synergy·José I Muñoz-BarúsManuel Febrero-Bande
Nov 26, 2009·International Journal of Legal Medicine·Gudrun HøisethJørg Mørland
Dec 4, 2009·Forensic Science International : Synergy·Simon ElliottDiane Cassidy
Feb 13, 2010·Forensic Science, Medicine, and Pathology·Elisabeth E Turk
Mar 3, 2010·Forensic Science International : Synergy·S UnkrigBurkhard Madea
Apr 1, 2010·Drug Testing and Analysis·Vincent Marks
Jul 10, 2010·Toxicology Mechanisms and Methods·R J Dinis-OliveiraT Magalhães
Jul 20, 2010·Forensic Science International : Synergy·Nilesh Keshav TumramAnand Paikuji Dongre
Jul 29, 2010·Journal of Analytical Toxicology·Gudrun HøisethAsbjørg Christophersen
Aug 6, 2010·Forensic Science International : Synergy·Ugo Da Broi, Carlo Moreschi
Sep 30, 2010·International Journal of Legal Medicine·Cornelius HessBurkhard Madea
Oct 12, 2010·International Journal of Legal Medicine·F MusshoffBurkhard Madea
Mar 4, 2011·Forensic Science International : Synergy·Annette ThieraufWolfgang Weinmann
Apr 23, 2011·Forensic Science International : Synergy·S A BlanaBurkhard Madea
Jun 15, 2011·Clinical Chemistry and Laboratory Medicine : CCLM·Camille BoulagnonPhilippe Gillery
Jul 15, 2011·Forensic Science International : Synergy·Mario ThevisWilhelm Schänzer
Nov 22, 2011·Drug Testing and Analysis·Mario ThevisI Ojanperä
Mar 31, 2012·Journal of Forensic Sciences·Michael Heninger
Sep 18, 2012·Forensic Science International : Synergy·Elena LendoiroJosé I Muñoz-Barús
Sep 25, 2012·Forensic Science International : Synergy·Luo ZhuoLing Li
Oct 16, 2012·International Journal of Legal Medicine·Marc AugsburgerCristian Palmiere
May 21, 2013·Forensic Science International : Synergy·Krzysztof BańkaRoman Mądro
Aug 29, 2013·Journal of Forensic Sciences·Cristian PalmiereDominique Werner
Nov 23, 2013·Legal Medicine·Cristian Palmiere, Marc Augsburger
Jan 1, 2014·Forensic Science International : Synergy·Krzysztof BańkaGrzegorz Buszewicz
Feb 22, 2014·International Journal of Legal Medicine·Cristian PalmierePetr Hejna
Apr 29, 2014·Emergency Medicine Clinics of North America·Brian CorwellGeorge C Willis
May 27, 2014·Forensic Science International : Synergy·Cristian Palmiere, Dominique Werner
Jul 19, 2014·Forensic Science, Medicine, and Pathology·Cristian PalmiereEric Grouzmann
Sep 10, 2014·International Journal of Legal Medicine·Cristian Palmiere, Patrice Mangin
Dec 3, 2014·Journal of Forensic and Legal Medicine·Cristian Palmiere, Coraline Egger
Feb 3, 2015·Drug Testing and Analysis·Cristian PalmiereDaniel Bardy
Apr 7, 2015·Immunology and Allergy Clinics of North America·Merin Kuruvilla, David A Khan
Sep 30, 2015·Biomarker Insights·Bethany M BironJoanne L Lomas-Neira
Oct 12, 2015·Journal of Forensic and Legal Medicine·Rajanikanta SwainR M Pandey
Oct 16, 2015·International Journal of Legal Medicine·T KeltanenK Lindroos
Dec 15, 2015·Science & Justice : Journal of the Forensic Science Society·Ankita K Parmar, Shobhana K Menon


Sep 7, 2016·Journal of Forensic and Legal Medicine·Cristian Palmiere
Aug 31, 2016·Forensic Science, Medicine, and Pathology·Roger W Byard
Sep 23, 2016·Journal of Clinical Pathology·William Patrick Tormey
May 17, 2018·Journal of Forensic Sciences·Mahra NourbakhshBamidele Adeagbo
Sep 11, 2017·Virchows Archiv : an International Journal of Pathology·Cristina BassoAssociation for European Cardiovascular Pathology
May 18, 2018·The American Journal of Forensic Medicine and Pathology·Melad G Paulis, Eman I Hasan
Apr 2, 2019·Journal of Forensic Sciences·Supawon SrettabunjongAnchalee Chittamma
Nov 27, 2018·The American Journal of Forensic Medicine and Pathology·Jack GarlandRexson Tse
May 17, 2019·The American Journal of Forensic Medicine and Pathology·Jack GarlandRexson Tse
Jun 23, 2020·Journal of Forensic Sciences·Mateusz TrokielewiczPiotr Maciejewicz
Jan 22, 2019·The American Journal of Forensic Medicine and Pathology·Sarah Hensby-BennettRexson Tse
Jul 7, 2017·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Robin E Ferner, Jeffrey K Aronson
Jun 17, 2020·Journal of Forensic Sciences·Yuqing JiaZhipeng Cao
Aug 7, 2018·Advances in Pharmacological Sciences·Abubakar DanmaigoroMd Zuki Abu Bakar
May 2, 2018·Diabetology & Metabolic Syndrome·Martin Roest ChristensenJytte Banner
Oct 31, 2019·Antibiotics·Lucia TattoliBiagio Solarino
Nov 28, 2020·Journal of Analytical Toxicology·Sarah M R Wille, Simon Elliott
Nov 19, 2020·Journal of Analytical Toxicology·Xiaomin ChenYan Jiang

Related Concepts

Blood Chemical Analysis
Legal Medicine Discipline
Hypothermia, Accidental
Myocardial Infarction
Livor Mortis

Related Feeds


Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.