Postnatal development of type II collagen and aggrecan mRNA expression in a rabbit craniomandibular joint

The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology
Jianying FengYi Fan

Abstract

The aim of this study was to investigate the postnatal growth changes in the condyle and disc of the rabbit craniomandibular joint (CMJ). Forty-eight rabbits from newborn to an age of 120 days were divided into eight groups, and chondrocytic differentiation and function were evaluated within the CMJ by in situ hybridization of type II collagen and aggrecan mRNA. The morphology of the posterior band and the bilaminar zone were similar in the newborn group and were composed primarily of mesenchymal cells and capillaries. After weaning, mastication loading induced the differentiation of mesenchymal cells, which was accompanied by structural differentiation between the posterior band and the bilaminar zone. Aggrecan first appeared in the posterior band of the disc at 30 days postnatally, when the rabbits began to masticate solid food. Type II collagen emerged in the disc at the age of 45 days. Both genes coexpressed in the deeper half of the proliferative layer, the whole hypertrophic layer, and the mineralized layer of the condylar cartilage and staining intensity increased with age. The coexpression of aggrecan and Type II collagen indicates the maturation of chondrocyte differentiation in the disc and condyle, which contributes ...Continue Reading

References

Apr 1, 1992·Archives of Oral Biology·N B Nagy, J C Daniel
Apr 1, 1991·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·S B MilamD Herbert
Jan 1, 1991·Archives of Oral Biology·N B Nagy, J C Daniel
Aug 1, 1995·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·L C DijkgraafR S Liem
Aug 1, 1997·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Q ZhaoB De Crombrugghe
Apr 16, 1998·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·M A CremerA H Kang
Apr 11, 2002·Cell Research·Chris KianiBurton B Yang
Apr 16, 2002·Molecular Pathology : MP·J I SiveA J Freemont
Feb 13, 2003·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Mohamed SharawyWon-Seok Choi
Sep 11, 2003·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Q HuangH Tideman
Apr 2, 2004·European Journal of Oral Sciences·Myriam DelatteAnne M Kuijpers-Jagtman
Mar 8, 2005·Matrix Biology : Journal of the International Society for Matrix Biology·Michael S DetamoreKyriacos A Athanasiou
Sep 28, 2005·Histochemistry and Cell Biology·Naoko ToriyaItaru Mizoguchi
Jun 15, 2006·Tissue Engineering·Alejandro J Almarza, Kyriacos A Athanasiou
May 16, 2007·Osteoarthritis and Cartilage·T KurthE B Hunziker
Jul 24, 2007·The Journal of Experimental Biology·Adamantios ArampatzisKirsten Albracht
Feb 21, 2008·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Masahiro NiwanoTakeyasu Maeda

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Q HuangH Tideman
Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Michael S DetamoreKyriacos A Athanasiou
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
Zhi-yuan GuYin-kai Zhang
© 2021 Meta ULC. All rights reserved