Postnatal Lifestyle Intervention for Overweight Women With Previous Gestational Diabetes: A Randomized Controlled Trial

The Journal of Clinical Endocrinology and Metabolism
Valerie A HolmesPAIGE Study Group

Abstract

Gestational diabetes mellitus (GDM) is associated with a sevenfold increased lifetime risk of type 2 diabetes. Excessive gestational weight gain and postpartum weight retention are established predictors of long-term obesity. To determine the impact of a postnatal lifestyle intervention program for overweight women with previous gestational diabetes mellitus (PAIGE). Postnatal overweight women with previous GDM participated in a multicenter randomized controlled trial between June 2013 and December 2014. The intervention comprised a 1-hour educational program, a free 3-month referral to a commercial weight management organization (Slimming World), a pedometer, and structured telephone and text support, in addition to usual care. The control group received usual care only. The primary outcome was weight loss at 6 months. Sixty women were randomized (29 intervention; 31 control) in two centers based on their week of attendance. The intervention group demonstrated significant weight loss at 6 months after randomization compared with the control group: mean ±SD, 3.9 ± 7.0 kg vs 0.7 ±3.8 kg (P = 0.02). Blood glucose levels did not significantly differ. With respect to well-being measures, a bodily pain was significantly reduced in t...Continue Reading

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Citations

Jan 9, 2020·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Siew LimSharleen O'Reilly
Aug 6, 2020·Journal of Clinical Medicine·Rhonda GaradSiew Lim
Aug 18, 2018·Current Diabetes Reports·Deirdre K Tobias
Dec 15, 2020·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Ninghua LiXilin Yang
May 18, 2021·American Journal of Preventive Medicine·Madhuri PalnatiLisa Chasan-Taber
Sep 17, 2021·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Mingling ChenSiew Lim

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